Roles for LBP and soluble CD14 in cellular uptake of LPS

被引：0

作者：

Tapping, RI ^{[1
]}

Gegner, JA ^{[1
]}

Kravchenko, VV ^{[1
]}

Tobias, PS ^{[1
]}

机构：

[1] Scripps Res Inst, Dept Immunol, La Jolla, CA 92037 USA

来源：

ENDOTOXIN AND SEPSIS: MOLECULAR MECHANISMS OF PATHOGENESIS, HOST RESISTANCE, AND THERAPY | 1998年 / 397卷

关键词：

D O I：

暂无

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Roles for LBP and CD14 in the LPS dependent activation of a wide variety of cells have been established. In the work described here, we describe roles for these proteins in the binding and uptake of LPS by cells which express membrane CD14 and those which do not Surprisingly, cell activation and LPS uptake appear to be independent phenomena with different protein requirements.

引用

页码：73 / 78

页数：6

共 5 条

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[2]

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[5] LIPOPOLYSACCHARIDE-BINDING PROTEIN-MEDIATED COMPLEXATION OF LIPOPOLYSACCHARIDE WITH SOLUBLE CD14 [J].

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JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (18) :10482-10488

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