PNEUMOCOCCAL BACTEREMIA IN A VACCINATED PEDIATRIC SICKLE CELL DISEASE POPULATION

被引:19
作者
Ellison, Angela M. [1 ]
Ota, Kaede V. [3 ]
McGowan, Karin L. [3 ]
Smith-Whitley, Kim [2 ]
机构
[1] Univ Penn, Childrens Hosp Philadelphia, Perelman Sch Med, Div Emergency Med, Philadelphia, PA 19104 USA
[2] Univ Penn, Childrens Hosp Philadelphia, Perelman Sch Med, Div Hematol, Philadelphia, PA 19104 USA
[3] Univ Penn, Childrens Hosp Philadelphia, Perelman Sch Med, Dept Pathol & Lab Med, Philadelphia, PA 19104 USA
关键词
pneumococcal polysaccharide vaccine; pneumococcal heptavalent vaccine; penicillin prophylaxis; PENICILLIN PROPHYLAXIS; CONJUGATE VACCINE; STREPTOCOCCUS-PNEUMONIAE; POLYSACCHARIDE VACCINE; ANTIBODY-RESPONSES; CHILDREN; ANEMIA; INFECTIONS; ERA;
D O I
10.1097/INF.0b013e3182480fed
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The incidence of pneumococcal disease in sickle cell disease declined significantly with penicillin prophylaxis as well as with the pneumococcal polysaccharide and heptavalent conjugate vaccines. In this report, we describe our experience with pneumococcal bacteremia in pediatric patients with sickle cell disease in the post-heptavalent pneumococcal conjugate vaccine era. Despite established prophylactic strategies, pneumococcal bacteremia continues to occur in patients with sickle cell disease.
引用
收藏
页码:534 / 536
页数:4
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