Fallacies of Evidence-Based Medicine in Cardiovascular Medicine

被引：5

作者：

Meier, Bernhard ^{[1
]}

Nietlispach, Fabian ^{[2
]}

机构：

[1] Univ Hosp Bern, Cardiol, Cardiovasc Dept, Bern, Switzerland

[2] Univ Hosp Zurich, Dept Cardiol, Univ Heart Ctr, Zurich, Switzerland

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2019年 / 123卷 / 04期

关键词：

PATENT FORAMEN OVALE; PERCUTANEOUS CLOSURE; CRYPTOGENIC STROKE; USERS GUIDES; THERAPY; MIGRAINE;

D O I：

10.1016/j.amjcard.2018.11.004

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Evidence-based medicine (EBM) has gained a dominant role as the backbone of modern medical activities since its definition about 20 years ago. It serves the purpose to unify and optimize patient management and minimize scientific bias and fraud. The article looks, in the realm of cardiovascular medicine, at the banes of overly rigorous application of EBM with insufficient counterbalancing of other decision criteria. It exemplifies based on fictitious and real trials where EBM does not make sense, can be misleading, or has been inappropriately applied. Closure of the patent foramen ovale and percutaneous coronary intervention are focused upon as 2 major examples. Without abrogating the merits of EBM, concern has to be raised about the risk of increasingly putting EBM first. Neglecting experience and common sense in patient-management as a consequence is not in the interest of mankind.

引用

页码：690 / 694

页数：5

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