Metallization of a Genetically Engineered Polypeptide

被引：3

作者：

Carlsen, Autumn ^{[1
]}

Higashiya, Seiichiro ^{[2
]}

Topilina, Natasha I. ^{[2
]}

Dunn, Kathleen A. ^{[1
]}

Geer, Robert E. ^{[1
]}

Eisenbraun, Eric T. ^{[1
]}

Kaloyeros, Alain E. ^{[1
]}

Welch, John T. ^{[2
]}

机构：

[1] SUNY Albany, CNSE, Albany, NY 12203 USA

[2] SUNY Albany, Dept Chem, Albany, NY 12222 USA

来源：

MACROMOLECULAR BIOSCIENCE | 2012年 / 12卷 / 02期

关键词：

biomimetic; genetic engineering; metallization; polypeptides; transmission electron microscopy; TOBACCO-MOSAIC-VIRUS; ASSEMBLED PEPTIDE FIBRILS; METAL NANOPARTICLES; DNA; NANOWIRES; DESIGN; TEMPLATES; NANOTUBES; PARTICLES; ARRAYS;

D O I：

10.1002/mabi.201100245

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recently, well-ordered biological materials have been exploited to pattern inorganic nanoparticles into linear arrays that are of particular interest for nanoelectronic applications. In this work, a de novo designed E. coli-expressed polypeptide (previously shown to form highly rectilinear, beta-sheet-containing structures) operates as a template for divalent metal cations. EDX and TEM analysis verify the attachment of platinum ions to the histidine-rich fibril surface, which was designed specifically to facilitate attachment of chemical moieties. Following chemical reduction, TEM further confirms the formation of localized zero-valent metal aggregates with sub-nanometer interparticle spacing.

引用

页码：269 / 273

页数：5

共 62 条

[1] Assembling materials with DNA as the guide [J].