tsRNAs: The Swiss Army Knife for Translational Regulation

被引：69

作者：

Shi, Junchao ^{[1
]}

Zhang, Yunfang ^{[1
,2
]}

Zhou, Tong ^{[1
]}

Chen, Qi ^{[1
]}

机构：

[1] Univ Nevada, Reno Sch Med, Dept Physiol & Cell Biol, Reno, NV 89557 USA

[2] Army Med Univ, Xinqiao Hosp, Res Ctr, Dept Hematol, Chongqing 40037, Peoples R China

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 2019年 / 44卷 / 03期

关键词：

TRANSFER-RNA;

D O I：

10.1016/j.tibs.2018.09.007

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

tRNA-derived small RNAs (tsRNAs, or tRFs) are a new category of regulatory noncoding RNAs with versatile functions. Recent emerging studies have begun to unveil distinct features of tsRNAs based on their sequence, RNA modifications, and structures that differentially impact their functions towards regulating multiple aspects of translational control and ribosome biogenesis.

引用

页码：185 / 189

页数：6

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