Type does matter. Use VIRGIN olive oil as your preferred fat to reduce your risk of breast cancer: case-control EpiGEICAM study

被引：2

作者：

Donat-Vargas, Carolina ^{[1
,2
,3
]}

Guerrero-Zotano, Angel ^{[4
]}

Lope, Virginia ^{[5
,6
]}

Bermejo, Begona ^{[7
]}

Casas, Ana ^{[8
]}

Baena-Canada, Jose Manuel ^{[9
,10
]}

Antolin, Silvia ^{[11
]}

Sanchez-Rovira, Pedro ^{[12
]}

Anton, Antonio ^{[13
]}

Garcia-Saenz, Jose Angel ^{[14
]}

Ramos, Manuel ^{[15
]}

Munoz, Montserrat ^{[16
,17
]}

de Juan, Ana ^{[18
]}

Jara Sanchez, Carlos ^{[19
]}

Chacon, Jose Ignacio ^{[20
]}

Gil-Gil, Miguel ^{[21
]}

Andres Conejero, Raquel ^{[22
]}

Llombart, Antonio ^{[23
]}

Bezares, Susana ^{[24
]}

Fernandez de Larrea-Baz, Nerea ^{[5
,6
]}

Perez-Gomez, Beatriz ^{[5
,6
]}

Martin, Miguel ^{[25
,26
]}

Pollan, Marina ^{[5
,6
]}

机构：

[1] CEI UAM CSIC, IMDEA Food Inst, Madrid, Spain

[2] Univ Autonoma Madrid, CIBERESP CIBER Epidemiol & Publ Hlth, Dept Prevent Med & Publ Hlth, IdiPaz,Sch Med, Madrid, Spain

[3] Karolinska Inst, Inst Environm Med, Unit Cardiovasc & Nutr Epidemiol, Stockholm, Sweden

[4] Inst Valenciano Oncol, Med Oncol Unit, Valencia, Spain

[5] Inst Salud Carlos III ISCII, Natl Ctr Epidemiol, Madrid, Spain

[6] Inst Salud Carlos III ISCII, Consortium Biomed Res Epidemiol & Publ Hlth CIBER, Madrid, Spain

[7] Hosp Clin, Med Oncol Unit, Valencia, Spain

[8] Hosp Virgen Rocio, Med Oncol Unit, Seville, Spain

[9] Hosp Puerta del Mar, Med Oncol Unit, Cadiz, Spain

[10] Inst Invest Biomed Cadiz INiBICA, Cadiz, Spain

[11] Complejo Hosp Univ Coruna, Med Oncol Unit, Coruna, Spain

[12] Inst Invest Biomed Cadiz INiBICA, Cadiz, Spain

[13] Complejo Hosp Univ Coruna, Med Oncol Unit, Coruna, Spain

[14] Hosp Univ Jaen, Med Oncol Unit, Jaen, Spain

[15] Hosp Univ Miguel Servet, Med Oncol Unit, Zaragoza, Spain

[16] Hosp Clin Univ San Carlos, Med Oncol Unit, Madrid, Spain

[17] Ctr Oncol Galicia, Med Oncol Unit, La Coruna, Spain

[18] Hosp Clin Barcelona, Med Oncol Unit, Barcelona, Spain

[19] Inst Invest Biomed Pi i Sunyer IDIBAPS, Translat Genom & Targeted Therapeut, Barcelona, Spain

[20] Hosp Marques Valdecilla, Med Oncol Unit, Santander, Spain

[21] Univ Rey Juan Carlos, Hosp Univ Fdn Alcorcon, Dept Especialidades Med, Med Oncol Unit, Madrid, Spain

[22] Hosp Clin Lozano Blesa, Med Oncol Unit, Zaragoza, Spain

[23] Hosp Arnau Vilanova, Med Oncol Unit, Valencia, Spain

[24] GEICAM Spanish Breast Canc Grp, Madrid, Spain

[25] Univ Complutense, Inst Invest Sanitaria Gregorio Maranon, Med Oncol Unit, Madrid, Spain

[26] CIBERONC ISCIII, Ctr Invest Biomed Red Oncol, Madrid, Spain

来源：

EUROPEAN JOURNAL OF CLINICAL NUTRITION | 2022年 / 76卷 / 09期

关键词：

MEDITERRANEAN DIET; IN-VITRO; PATTERNS;

D O I：

10.1038/s41430-022-01101-w

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

The Epi-GEICAM study comprises 1017 invasive BC cases matched with controls of similar age (49 +/- 9 years) and residence. Diet and OO consumption were collected through a validated food frequency questionnaire. 75% of women referred OO, common (refined) or virgin, as the main fat source. Using conditional logistic regression models, we compared different scenarios of type and frequency of OO consumption, using as reference those women not always using OO for the three culinary practices (seasoning, cooking, and frying) and adding <2 tablespoons (tbsps.) per day during the meal to bread, salad, or dishes. A substantial inverse association was observed in those women always using VOO for the three culinary practices and consuming >= 2 tbsps. of OO per day during meals (adjusted OR, 0.72; 95% CI: 0.51, 1.03; P = 0.07). Potential benefits from OO consumption, at least as regards the protection provided for BC, could be mostly conferred with VOO, and when its consumption is high.

引用

页码：1343 / 1346

页数：4

共 23 条

[1] The olive oil phenolic (-)-oleocanthal modulates estrogen receptor expression in luminal breast cancer in vitro and in vivo and synergizes with tamoxifen treatment [J].

Ayoub, Nehad M. ;

Siddique, Abu Bakar ;

Ebrahim, Hassan Y. ;

Mohyeldin, Mohamed M. ;

El Sayed, Khalid A. .

EUROPEAN JOURNAL OF PHARMACOLOGY, 2017, 810 :100-111

[2] Phytochemistry - Ibuprofen-like activity in extra-virgin olive oil [J].

Beauchamp, GK ;

Keast, RSJ ;

Morel, D ;

Lin, JM ;

Pika, J ;

Han, Q ;

Lee, CH ;

Smith, AB ;

Breslin, PAS .

NATURE, 2005, 437 (7055) :45-46

[3] Spanish Mediterranean diet and other dietary patterns and breast cancer risk: case-control EpiGEICAM study [J].

Castello, A. ;

Pollan, M. ;

Buijsse, B. ;

Ruiz, A. ;

Casas, A. M. ;

Baena-Canada, J. M. ;

Lope, V. ;

Antolin, S. ;

Ramos, M. ;

Munoz, M. ;

Lluch, A. ;

de Juan-Ferre, A. ;

Jara, C. ;

Jimeno, M. A. ;

Rosado, P. ;

Diaz, E. ;

Guillem, V. ;

Carrasco, E. ;

Perez-Gomez, B. ;

Vioque, J. ;

Boeing, H. ;

Martin, M. .

BRITISH JOURNAL OF CANCER, 2014, 111 (07) :1454-1462

[4] Extra-virgin olive oil contains a metabolo-epigenetic inhibitor of cancer stem cells [J].

Corominas-Faja, Bruna ;

Cuyas, Elisabet ;

Lozano-Sanchez, Jesus ;

Cufi, Silvia ;

Verdura, Sara ;

Fernandez-Arroyo, Salvador ;

Borras-Linares, Isabel ;

Martin-Castillo, Begona ;

Martin, Angel G. ;

Lupu, Ruth ;

Nonell-Canals, Alfons ;

Sanchez-Martinez, Melchor ;

Micol, Vicente ;

Joven, Jorge ;

Segura-Carretero, Antonio ;

Menendez, Javier A. .

CARCINOGENESIS, 2018, 39 (04) :601-613

[5] Dietary Patterns and Risk of Invasive Ductal and Lobular Breast Carcinomas: A Systematic Review and Meta-analysis [J].

Dianatinasab, Mostafa ;

Rezaian, Marjan ;

HaghighatNezad, Elmira ;

Bagheri-Hosseinabadi, Zahra ;

Amanat, Sasan ;

Rezaeian, Shahab ;

Masoudi, Alireza ;

Ghiasvand, Reza .

CLINICAL BREAST CANCER, 2020, 20 (04) :E516-E528

[6] The Bitter Taste of Extra Virgin Olive Oil for a Sweet Long Life [J].

Estruch, Ramon ;

Lamuela-Raventos, Rosa M. ;

Ros, Emilio .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2020, 75 (15) :1740-1742

[7] Virgin Olive Oil and Health: Summary of the III International Conference on Virgin Olive Oil and Health Consensus Report, JAEN (Spain) 2018 [J].

Gaforio, Jose J. ;

Visioli, Francesco ;

Alarcon-de-la-Lastra, Catalina ;

Castaner, Olga ;

Delgado-Rodriguez, Miguel ;

Fito, Monserrat ;

Hernandez, Antonio F. ;

Huertas, Jesus R. ;

Martinez-Gonzalez, Miguel A. ;

Menendez, Javier A. ;

de la Osada, Jesus ;

Papadaki, Angeliki ;

Parron, Tesifon ;

Pereira, Jorge E. ;

Rosillo, Maria A. ;

Sanchez-Quesada, Cristina ;

Schwingshackl, Lukas ;

Toledo, Estefania ;

Tsatsakis, Aristidis M. .

NUTRIENTS, 2019, 11 (09)

[8] Absorption, Distribution, Metabolism, and Excretion of the Main Olive Tree Phenols and Polyphenols: A Literature Review [J].

Galmes, Sebastia ;

Reynes, Barbara ;

Palou, Mariona ;

Palou-March, Andreu ;

Palou, Andreu .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 69 (18) :5281-5296

[9] Reduction in the risk of human breast cancer by selective cyclooxygenase-2 (COX-2) inhibitors [J].

Harris, RE ;

Beebe-Donk, J ;

Alshafie, GA .

BMC CANCER, 2006, 6 (1)

[10] Overeating, caloric restriction and breast cancer risk by pathologic subtype: the EPIGEICAM study [J].

Lope, Virginia ;

Martin, Miguel ;

Castello, Adela ;

Ruiz, Amparo ;

Casas, Ana M. ;

Manuel Baena-Canada, Jose ;

Antolin, Silvia ;

Ramos-Vazquez, Manuel ;

Angel Garcia-Saenz, Jose ;

Munoz, Montserrat ;

Lluch, Ana ;

de Juan-Ferre, Ana ;

Jara, Carlos ;

Sanchez-Rovira, Pedro ;

Anton, Antonio ;

Ignacio Chacon, Jose ;

Arcusa, Angels ;

Angeles Jimeno, Ma ;

Bezares, Susana ;

Vioque, Jesus ;

Carrasco, Eva ;

Perez-Gomez, Beatriz ;

Pollan, Marina .

SCIENTIFIC REPORTS, 2019, 9 (1)

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