Enzymatic resolution of p-amino methyl esters using lipase B from Candida antarctica

被引：0
|
作者：
Escalante, Jaime [1 ]
机构：
[1] UAEM, Ctr Invest Quim, Cuernavaca 62210, Morelos, Mexico
来源：
RECENT DEVELOPMENTS IN PHYSICAL CHEMISTRY | 2008年 / 979卷
关键词：
enzymatic catalysis; Cal-B; beta-amino acids; CATALYZED MICHAEL ADDITION; ORGANIC MEDIA; ACID; HYDROLYSIS; ALCOHOLS;
D O I：
暂无
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
We report the enzymatic resolution of methyl 3-aminobutanoate and methyl 3-amino-3-phenylpropanoate derivatives, with the amine protected with groups such as Bz, Cbz, Boc, Fmoc and aminobenzamide (ABA). The resolutions were carried out through transesterifications catalyzed by lipase B from Candida antarctica (Cal-B). The reactions proceeded with a high conversion and yielded optically pure enantiomers.
引用
收藏
页码：60 / 67
页数：8
相关论文
共 50 条
  • [1] Enzymatic resolution of N-protected-β3 -amino methyl esters, using lipase B from Candida antarctica
    Flores-Sánchez, P
    Escalante, J
    Castillo, E
    TETRAHEDRON-ASYMMETRY, 2005, 16 (03) : 629 - 634
  • [2] Enzymatic synthesis of quercetin oleate esters using Candida antarctica lipase B
    Amy Yi Hsan Saik
    Yau Yan Lim
    Johnson Stanslas
    Wee Sim Choo
    Biotechnology Letters, 2017, 39 : 297 - 304
  • [3] Enzymatic synthesis of quercetin oleate esters using Candida antarctica lipase B
    Saik, Amy Yi Hsan
    Lim, Yau Yan
    Stanslas, Johnson
    Choo, Wee Sim
    BIOTECHNOLOGY LETTERS, 2017, 39 (02) : 297 - 304
  • [4] Candida antarctica lipase A -: a powerful catalyst for the resolution of heteroaromatic β-amino esters
    Solymár, M
    Fülöp, F
    Kanerva, LT
    TETRAHEDRON-ASYMMETRY, 2002, 13 (21) : 2383 - 2388
  • [5] Enzymatic resolution of racemic secondary alcohols by lipase B from Candida antarctica
    Patel, RN
    Banerjee, A
    Nanduri, V
    Goswami, A
    Comezoglu, FT
    JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 2000, 77 (10) : 1015 - 1019
  • [6] Enzymatic resolution of bicyclic 1-heteroarylamines using Candida antarctica lipase B
    Skupinska, KA
    McEachern, EJ
    Baird, IR
    Skerlj, RT
    Bridger, GJ
    JOURNAL OF ORGANIC CHEMISTRY, 2003, 68 (09): : 3546 - 3551
  • [7] Directed evolution of Candida antarctica lipase B for kinetic resolution of profen esters
    Qin, Bin
    Liang, Ping
    Jia, Xian
    Zhang, Xin
    Mu, Mao
    Wang, Xiao-Ying
    Ma, Guo-Zhen
    Jin, Dan-Ni
    You, Song
    CATALYSIS COMMUNICATIONS, 2013, 38 : 1 - 5
  • [8] Structural effects on chemo- and enantio-selectivity of Candida antarctica lipase B -: Resolution of β-amino esters
    Gedey, S
    Liljeblad, A
    Lázár, L
    Fülöp, F
    Kanerva, LT
    CANADIAN JOURNAL OF CHEMISTRY, 2002, 80 (06) : 565 - 570
  • [9] ENZYMATIC PRODUCTION OF ETHYL OLEATE ESTER USING A LIPASE FROM Candida antarctica B
    Neta, N. S.
    Cunha, J. A. C.
    Sancho, S. O.
    Abreu, R. F. A.
    Pontes, D. F.
    Carioca, J. O. B.
    Rodrigues, L. R.
    Teixeira, J. A.
    HOLOS, 2012, 28 (02) : 22 - 33
  • [10] Preparation of highly enantiopure β-amino esters by Candida antarctica lipase A
    Gedey, S
    Liljeblad, A
    Lázár, L
    Fülöp, F
    Kanerva, LT
    TETRAHEDRON-ASYMMETRY, 2001, 12 (01) : 105 - 110
12345