Serum β-endorphin levels in morbidly obese patients:: The effect of vertical banded gastroplasty

被引:3
|
作者
Karayiannakis, AJ
Zbar, A
Makri, GG
Syrigos, K
Athanasiadis, L
Alexiou, D
Bastounis, EA
机构
[1] Univ Athens, Laikon Hosp, Dept Surg 1, Athens, Greece
[2] Royal Postgrad Med Sch, Dept Surg, London, England
[3] Univ Athens, Laikon Hosp, Dept Internal Med 1, Endocrinol Unit, Athens, Greece
[4] Univ London St Georges Hosp, Sch Med, Dept Psychiat, London SW17 0RE, England
关键词
beta-endorphin; morbid obesity; surgery; vertical banded gastroplasty; weight loss;
D O I
10.1159/000008606
中图分类号
R61 [外科手术学];
学科分类号
摘要
The associations between serum beta-endorphin levels and clinical and metabolic variables as well as beta-endorphin changes after surgically induced weight loss were investigated in 13 morbidly obese patients. A significant positive correlation between beta-endorphin and body weight, degree of body weight increase and ACTH was found preoperatively. Only body weight was independently associated with beta-endorphin levels, Twelve months following vertical banded gastroplasty, there was an extensive weight loss in all patients and improvement in their metabolic profile. A significant reduction in P-endorphin levels which was proportional to the extent of weight loss was also observed.
引用
收藏
页码:409 / 413
页数:5
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