Fabry disease and Factor V Leiden: a potent vascular risk combination

被引:4
作者
Tchan, M. [1 ]
Sillence, D. [1 ]
机构
[1] Childrens Hosp Westmead, Dept Clin Genet, Sydney, NSW, Australia
关键词
Fabry disease; Factor V Leiden; stroke; ENZYME REPLACEMENT THERAPY; CEREBRAL HYPERPERFUSION; ALPHA-GALACTOSIDASE; CARDIAC MANIFESTATIONS; GENETIC MODIFIERS; LESIONS; REVERSAL; STROKE; SAFETY;
D O I
10.1111/j.1445-5994.2011.02483.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 45-year-old man with heterozygous Factor V Leiden presented with his third cerebrovascular accident despite being on warfarin at a therapeutic international normalized ratio. Subsequent investigation revealed a second genetic diagnosis of Fabry disease. He then had an acute myocardial infarction whilst on aspirin and warfarin.
引用
收藏
页码:422 / 426
页数:5
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