Stereoselective Synthesis of (Z)-1,2-Dithio-1-alkenes via Copper-Catalyzed Thiolation of (Z)-2-Bromovinyl Sulfides

被引：2

作者：

Xu, Hui ^{[1
]}

Chen, Wanzhi ^{[1
]}

Chen, Jiuxi ^{[2
]}

Wu, Huayue ^{[2
]}

机构：

[1] Zhejiang Univ, Dept Chem, Hangzhou 310028, Zhejiang, Peoples R China

[2] Wenzhou Univ, Coll Chem & Mat Engn, Wenzhou 325035, Peoples R China

来源：

SYNTHESIS-STUTTGART | 2012年 / 44卷 / 03期

关键词：

copper catalyst; cross-coupling; thiolation; (Z)-2-bromovinyl sulfide; (Z)-1,2-dithio-1-alkene; CROSS-COUPLING REACTIONS; TERMINAL ALKYNES; C-S; VINYL SULFIDES; DIARYL DISULFIDES; CESIUM HYDROXIDE; BOND FORMATION; ARYL IODIDES; THIOLS; PALLADIUM;

D O I：

10.1055/s-0031-1290067

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We describe a new method for the stereoselective synthesis of (Z)-1,2-dithio-1-alkenes via copper-catalyzed cross-coupling of (Z)-2-bromovinyl sulfides and thiols. The desired products are obtained in good to excellent yields. The double bond geometry of the starting (Z)-2-bromovinyl sulfides is retained under these reaction conditions.

引用

页码：380 / 388

页数：9

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