Regioselective direct arylation of indoles on the benzenoid moiety

被引：138

作者：

Yang, Youqing ^{[1
]}

Shi, Zhuangzhi ^{[1
]}

机构：

[1] Nanjing Univ, Sch Chem & Chem Engn, State Key Lab Coordinat Chem, Nanjing 210023, Jiangsu, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2018年 / 54卷 / 14期

关键词：

H BOND FUNCTIONALIZATION; CATALYZED DIRECT ARYLATION; DUAL C-H; ROOM-TEMPERATURE; C-3; ARYLATION; 2-SUBSTITUTED INDOLES; SELECTIVE ARYLATION; N-PIVALOYLINDOLES; DICTYODENDRINS F; ORTHO-METALATION;

D O I：

10.1039/c7cc08752g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Recent advances in transition metal-catalyzed selective C-H functionalization of indoles have garnered tremendous attention. Great efforts have been devoted to C2 and C3 arylation because of the inherent reactivity of the pyrrole ring. Until recently, elegant methods have been developed to enable selective direct arylation on the benzenoid moiety at C4, C5, C6, and C7. This review highlights the contributions made in benzenoid direct arylation of indoles and presents their potential in organic synthesis.

引用

页码：1676 / 1685

页数：10

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