Electrical and Mechanical Ventricular Activation During Left Bundle Branch Block and Resynchronization

被引：47
作者：
Strik, Marc [1 ,3 ]
Regoli, Francois [2 ]
Auricchio, Angelo [2 ]
Prinzen, Frits [3 ]
机构：
[1] Maastricht Univ, Dept Physiol, NL-6200 MD Maastricht, Netherlands
[2] Fdn Cardioctr Ticino, Lugano Ticino, Switzerland
[3] Maastricht Univ, Dept Physiol, Cardiovasc Res Inst Maastricht, NL-6200 MD Maastricht, Netherlands
来源：
JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH | 2012年 / 5卷 / 02期
关键词：
Left bundle branch block; Cardiac resynchronization therapy; Electrical mapping; CARDIAC MAGNETIC-RESONANCE; HEART-FAILURE PATIENTS; MYOCARDIAL SCAR; SPECKLE-TRACKING; QRS DURATION; CONDUCTION DISTURBANCES; ISCHEMIC CARDIOMYOPATHY; ENDOCARDIAL ACTIVATION; LONGITUDINAL STRAIN; PREDICTS RESPONSE;
D O I：
10.1007/s12265-012-9351-1
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Cardiac resynchronization therapy (CRT) aims to treat selected heart failure patients suffering from conduction abnormalities with left bundle branch block (LBBB) as the culprit disease. LBBB remained largely underinvestigated until it became apparent that the amount of response to CRT was heterogeneous and that the therapy and underlying pathology were thus incompletely understood. In this review, current knowledge concerning activation in LBBB and during biventricular pacing will be explored and applied to current CRT practice, highlighting novel ways to better measure and treat the electrical substrate.
引用
收藏
页码：117 / 126
页数：10
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