Host defense against malaria favors Salmonella

被引：6
|
作者：
MacLennan, Calman A. [1 ]
机构：
[1] Novartis Vaccines Inst Global Hlth, Siena, Italy
来源：
NATURE MEDICINE | 2012年 / 18卷 / 01期
基金：
英国医学研究理事会;
关键词：
HEME OXYGENASE-1; INFECTIONS; PROTECTION; BACTEREMIA; CHILDREN; AFRICA; MICE;
D O I：
10.1038/nm.2636
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The beneficial cytoprotective effects of heme oxygenase-1 (HO-1) in malaria infection are counterpoised by higher susceptibility to nontyphoidal Salmonella (NTS) bacteremia. A new study in mice co-infected with malaria and Salmonella provides a mechanism for the long-recognized association between malaria and NTS infection in African children. © 2012 Nature America, Inc. All rights reserved.
引用
收藏
页码：21 / 22
页数：2
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