Comparative genome analysis of the first Listeria monocytogenes core genome multi-locus sequence types CT2050 AND CT2051 strains with their close relatives

被引：0

作者：

Nwaiwu, Ogueri ^{[1
]}

机构：

[1] Univ Nottingham, Sch Biosci, Sutton Boninton Campus, Nottingham LE12 5RD, England

来源：

AIMS MICROBIOLOGY | 2022年 / 8卷 / 01期

关键词：

Listeria monocytogenes; pan-genome; antimicrobial resistance genes; plasmid; bacitracin genes; genomics; RESISTANCE;

D O I：

10.3934/microbio1.2022006

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Genome sequences of the three strains of L. monocytogenes, which are the first core genome multi-locus sequence types (cgMLST) 2050 and 2051 were reviewed and compared with 21 close relatives and reference genomes. Using a pan-genomic approach to analyse whole genome sequences, it was found that the strains consisted of approximately 2200 shared genes and a much greater pool of genes present as an accessory genome. An unknown transmissible sequence of approximately 91 kb harbouring bacitracin resistance genes found in strain LmNG2 (1/2b) was revealed to be an Inc 18 plasmid. The cg2051, strain LmNG3 (1/2a) haboured more unique genes (252 vs 230) than the well-known reference strain LmEGD-e (1/2a). More studies to monitor new strains can help reduce food-borne outbreaks.

引用

页码：61 / 72

页数：12

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