Impact of Nodal Status and Tumor Burden in Sentinel Lymph Nodes on the Clinical Outcomes of Cancer Patients

被引：38

作者：

Leong, Stanley P. L. ^{[10
]}

Zuber, Markus ^{[1
]}

Ferris, Robert L. ^{[2
,3
,4
]}

Kitagawa, Yuko ^{[5
]}

Cabanas, Ramon ^{[6
]}

Levenback, Charles ^{[7
]}

Faries, Mark ^{[8
]}

Saha, Sukamal ^{[9
]}

机构：

[1] Univ Basel, Dept Surg, Kantonsspital Olten, Basel, Switzerland

[2] Univ Pittsburgh, Dept Otolaryngol, Pittsburgh, PA 15260 USA

[3] Univ Pittsburgh, Dept Radiat Oncol, Pittsburgh, PA USA

[4] Univ Pittsburgh, Dept Immunol, Pittsburgh, PA USA

[5] Keio Univ, Sch Med, Dept Surg, Tokyo 160, Japan

[6] Victory Mem Hosp, Dept Surg, Brooklyn, NY USA

[7] Univ Texas MD Anderson Canc Ctr, Dept Gynecol Oncol, Houston, TX 77030 USA

[8] Yale Univ, Sch Med, Dept Surg, New Haven, CT 06510 USA

[9] McLaren Reg Med Ctr, Dept Surg, Flint, MI USA

[10] Calif Pacific Med Ctr, Ctr Melonoma Res & Treatment, Melanoma Program, Calif Pacific Med & Res Inst,Dept Surg, San Francisco, CA 94115 USA

来源：

JOURNAL OF SURGICAL ONCOLOGY | 2011年 / 103卷 / 06期

关键词：

tumor burden; sentinel lymph nodes; outcomes; CELL LUNG-CANCER; POLYMERASE-CHAIN-REACTION; STAGE CERVICAL-CANCER; LOCALIZED PROSTATE-CANCER; SELECTIVE NECK DISSECTION; RISK ENDOMETRIAL CANCER; GASTRIC-CANCER; PROGNOSTIC-SIGNIFICANCE; COLON-CANCER; COLORECTAL-CANCER;

D O I：

10.1002/jso.21815

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The validation of sentinel lymph node (SLN) concept in melanoma and breast cancer has established a new paradigm in cancer metastasis that, in general, cancer cells spread in a orderly fashion from the primary site to the SLNs in the regional nodal basin and then to the distant sites. In this review article, we examine the development of SLN concept in penile carcinoma, melanoma and breast carcinoma and its application to other solid cancers with emphasis of the relationship between micrometastasis in SLNs and clinical outcomes. J. Surg. Oncol. 2011;103:518-530. (C) 2011 Wiley-Liss, Inc.

引用

页码：518 / 530

页数：13

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