Gamma Knife radiosurgery for acoustic Schwannoma: Effects of low radiation dose and functional prognosis

被引：38

作者：

Hirato, M ^{[1
]}

Inoue, H ^{[1
]}

Zama, A ^{[1
]}

Ohye, C ^{[1
]}

Shibazaki, T ^{[1
]}

Andou, Y ^{[1
]}

机构：

[1] GUNMA UNIV, SCH MED, HIDAKA HOSP, DEPT NEUROSURG, MAEBASHI, GUMMA 371, JAPAN

来源：

STEREOTACTIC AND FUNCTIONAL NEUROSURGERY | 1996年 / 66卷

关键词：

Gamma Knife radiosurgery; Schwannoma; acoustic neurinoma; hearing;

D O I：

10.1159/000099803

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The effects of relatively low dose Gamma Knife irradiation on acoustic schwannoma were evaluated in 29 patients followed over 2 years after treatment. The mean dose delivered to the tumor periphery was 12.1 Gy. Lowering of the magnetic resonance signal intensity in the tumor center appeared in 69% and signs of tumor shrinkage appeared in 59% of cases. The cyst in the tumor enlarged in 3 cases, and 2 cases developed hydrocephalus. The percentage of pure-tone hearing preservation was 82% at 3 months, 73% at 6 months, 68% at 12 months, 64% at 18 months and 59% at 24 months in 22 out of 29 cases. Relatively low dose Gamma Knife radiosurgery was effective in suppressing tumor growth, with preservation of hearing.

引用

页码：134 / 141

页数：8

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