Molecularly Imprinted Polymers and Surface Imprinted Polymers Based Electrochemical Biosensor for Infectious Diseases

被引：150

作者：

Cui, Feiyun ^{[1
]}

Zhou, Zhiru ^{[1
]}

Zhou, H. Susan ^{[1
]}

机构：

[1] Worcester Polytech Inst, Dept Chem Engn, 100 Inst Rd, Worcester, MA 01609 USA

来源：

SENSORS | 2020年 / 20卷 / 04期

基金：

美国国家科学基金会;

关键词：

molecularly imprinted polymers (MIPs); surface imprinted polymers (SIPs); electrochemical biosensor; biomarkers for infectious diseases; ULTRASENSITIVE DETECTION; SELECTIVE DETECTION; DOUBLE-TEMPLATES; LABEL-FREE; RECOGNITION; SENSOR; VIRUS; DIAGNOSIS; NANOPARTICLES; RECEPTORS;

D O I：

10.3390/s20040996

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Owing to their merits of simple, fast, sensitive, and low cost, electrochemical biosensors have been widely used for the diagnosis of infectious diseases. As a critical element, the receptor determines the selectivity, stability, and accuracy of the electrochemical biosensors. Molecularly imprinted polymers (MIPs) and surface imprinted polymers (SIPs) have great potential to be robust artificial receptors. Therefore, extensive studies have been reported to develop MIPs/SIPs for the detection of infectious diseases with high selectivity and reliability. In this review, we discuss mechanisms of recognition events between imprinted polymers with different biomarkers, such as signaling molecules, microbial toxins, viruses, and bacterial and fungal cells. Then, various preparation methods of MIPs/SIPs for electrochemical biosensors are summarized. Especially, the methods of electropolymerization and micro-contact imprinting are emphasized. Furthermore, applications of MIPs/SIPs based electrochemical biosensors for infectious disease detection are highlighted. At last, challenges and perspectives are discussed.

引用

页数：14

共 68 条

[1] In silico designed nanoMIP based optical sensor for endotoxins monitoring [J].

Abdin, M. J. ;

Altintas, Z. ;

Tothill, I. E. .

BIOSENSORS & BIOELECTRONICS, 2015, 67 :177-183

[2] Recent Advances in Electrochemical Sensors Based on Molecularly Imprinted Polymers and Nanomaterials [J].

Ait Lahcen, Abdellatif ;

Amine, Aziz .

ELECTROANALYSIS, 2019, 31 (02) :188-201

[3] Ultrasensitive detection of endotoxins using computationally designed nanoMIPs [J].

Altintas, Zeynep ;

Abdin, Mohammed J. ;

Tothill, Alexander M. ;

Karim, Kal ;

Tothill, Ibtisam E. .

ANALYTICA CHIMICA ACTA, 2016, 935 :239-248

[4] Comparative investigations for adenovirus recognition and quantification: Plastic or natural antibodies? [J].

Altintas, Zeynep ;

Pocock, Jack ;

Thompson, Katy-Anne ;

Tothill, Ibtisam E. .

BIOSENSORS & BIOELECTRONICS, 2015, 74 :996-1004

[5] Detection of Waterborne Viruses Using High Affinity Molecularly Imprinted Polymers [J].

Altintas, Zeynep ;

Gittens, Micah ;

Guerreiro, Antonio ;

Thompson, Katy-Anne ;

Walker, Jimmy ;

Piletsky, Sergey ;

Tothill, Lbtisam E. .

ANALYTICAL CHEMISTRY, 2015, 87 (13) :6801-6807

[6] Detection of candidaemia in patients with and without underlying haematological disease [J].

Arendrup, M. C. ;

Bergmann, O. J. ;

Larsson, L. ;

Nielsen, H. V. ;

Jarlov, J. O. ;

Christensson, B. .

CLINICAL MICROBIOLOGY AND INFECTION, 2010, 16 (07) :855-862

[7] A molecularly imprinted electrochemiluminescence sensor for ultrasensitive HIV-1 gene detection using EuS nanocrystals as luminophore [J].

Babamiri, Bahareh ;

Salimi, Abdollah ;

Hallaj, Rahman .

BIOSENSORS & BIOELECTRONICS, 2018, 117 :332-339

[8] A Double-Imprinted Diffraction-Grating Sensor Based on a Virus-Responsive Super-Aptamer Hydrogel Derived from an Impure Extract [J].

Bai, Wei ;

Spivak, David A. .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2014, 53 (08) :2095-2098

[9]

Cai D, 2010, NAT NANOTECHNOL, V5, P597, DOI [10.1038/nnano.2010.114, 10.1038/NNANO.2010.114]

[10] Molecular imprinting: perspectives and applications [J].

Chen, Lingxin ;

Wang, Xiaoyan ;

Lu, Wenhui ;

Wu, Xiaqing ;

Li, Jinhua .

CHEMICAL SOCIETY REVIEWS, 2016, 45 (08) :2137-2211

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