The evolving field of biodefence: Therapeutic developments and diagnostics

被引：118
作者：
Burnett, JC
Henchal, EA
Schmaljohn, AL
Bavari, S [1 ]
机构：
[1] NCI, Dev Therapeut Program, Based Drug Discovery Grp, SAIC, Frederick, MD 21702 USA
[2] USA, Med Res Inst Infect Dis, Frederick, MD 21702 USA
来源：
NATURE REVIEWS DRUG DISCOVERY | 2005年 / 4卷 / 04期
关键词：
D O I：
10.1038/nrd1694
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The threat of bioterrorism and the potential use of biological weapons against both military and civilian populations has become a major concern for governments around the world. For example, in 2001 anthrax-tainted letters resulted in several deaths, caused widespread public panic and exerted a heavy economic toll. If such a small-scale act of bioterrorism could have such a huge impact, then the effects of a large-scale attack would be catastrophic. This review covers recent progress in developing therapeutic countermeasures against, and diagnostics for, such agents.
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页码：281 / 297
页数：17
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