1,3-Dibromo-5,5-dimethylhydantoin as an efficient homogeneous catalyst for synthesis of benzoxazoles, benzimidazoles, and oxazolo[4,5-b]pyridines

被引：24

作者：

Hojati, Seyedeh Fatemeh ^{[1
]}

Maleki, Behrooz ^{[1
]}

Beykzadeh, Zahra ^{[1
]}

机构：

[1] Sabzevar Tarbiat Moallem Univ, Dept Chem, Sabzevar, Iran

来源：

MONATSHEFTE FUR CHEMIE | 2011年 / 142卷 / 01期

关键词：

1,3-Dibromo-5,5-dimethylhydantoin; Benzoxazole; Benzimidazole; Oxazolo[4,5-b] pyridine; Orthoester; SOLVENT-FREE CONDITIONS; 2-SUBSTITUTED BENZIMIDAZOLES; POLYPHOSPHORIC ACID; ROOM-TEMPERATURE; BENZOTHIAZOLES; DERIVATIVES; HETEROCYCLES; ZROCL2-CENTER-DOT-8H(2)O; REARRANGEMENT; CONDENSATION;

D O I：

10.1007/s00706-010-0412-3

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A simple and highly efficient method for synthesis of benzoxazoles, benzimidazoles, and oxazolo[4,5-b]pyridines is described. Condensation of orthoesters with o-substituted anilines or 2-amino-3-hydroxypyridine was performed in the presence of catalytic amounts of commercially available, inexpensive, and moisture-stable 1,3-dibromo-5,5-dimethylhydantoin under solvent-free conditions. The corresponding heterocycles were obtained in good to excellent yields. The main advantages of the present procedure are mild reaction conditions, short reaction times, high yields of products, easy work-up, and absence of solvent.

引用

页码：87 / 91

页数：5

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