Continuous 1H and 13C Signal Enhancement in NMR Spectroscopy and MRI Using Parahydrogen and Hollow-Fiber Membranes

被引：54

作者：

Roth, Meike ^{[1
]}

Kindervater, Petra ^{[1
]}

Raich, Hans-Peter ^{[1
]}

Bargon, Joachim ^{[2
]}

Spiess, Hans W. ^{[1
]}

Muennemann, Kerstin ^{[1
]}

机构：

[1] Max Planck Inst Polymer Res, D-55128 Mainz, Germany

[2] Univ Bonn, Inst Phys & Theoret Chem, D-5300 Bonn, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2010年 / 49卷 / 45期

关键词：

chemical selectivity; hyperpolarization; NMR spectroscopy; parahydrogen; polarization transfer; PARA-HYDROGEN; POLARIZATION; RESOLUTION;

D O I：

10.1002/anie.201002725

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Parahydrogen-induced polarization is used for the continuous generation of hyperpolarized molecules. Constant 1H and 13C NMR signal enhancement is demonstrated using a continuous delivery of parahydrogen by hollow fiber membranes (see picture, left), which allows the acquisition of two-dimensional NMR signals requiring multiple acquisitions with constant initial polarization. © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

收藏

页码：8358 / 8362

页数：5

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