A double-indole structure fluorescent probe for monitoring sulfur dioxide derivatives with distinct ratiometric fluorescence signals in mammalian cells

被引：15

作者：

Wang, Li ^{[1
]}

Yang, Wenge ^{[1
]}

Song, Yiyi ^{[1
]}

Gu, Yuanyun ^{[1
]}

Hu, Yonghong ^{[1
]}

机构：

[1] Nanjing Tech Univ, Coll Biotechnol & Pharmaceut Engn, 30 South Puzhu Rd, Nanjing 211816, Jiangsu, Peoples R China

来源：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2020年 / 225卷

关键词：

Fluorescent probe; Bisulfite; Colorimetric; Bioimaging; AQUEOUS-SOLUTION; SO2; DERIVATIVES; SELECTIVE DETECTION; SULFIDE; CYSTEINE; EXPRESSION; BISULFITE; TUMOR;

D O I：

10.1016/j.saa.2019.117495

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

Based on the addition reaction of the sulfur dioxide derivative to the C=C double bond, the probe HDI was designed and synthesized. The two-channel fluorescent probe HDI changed from orange to colorless and the fluorescence changed from red to blue when the bisulfite was detected. And the probe responds rapidly to bisulfite within 2 min, with high sensitivity and specificity. In addition, the probe can be used to detect the concentration of bisulfite with a low detection limit (80 nM). Cytological experiments have also demonstrated that probe HDI has low cytotoxicity and could be used for ratiometric detection of sulfur dioxide derivatives in living cells. (C) 2019 Elsevier B.V. All rights reserved.

引用

页数：7

共 39 条

[1] Endocrine-specific NIR fluorophores for adrenal gland targeting [J].

Ashitate, Yoshitomo ;

Levitz, Andrew ;

Park, Min Ho ;

Hyun, Hoon ;

Venugopal, Vivek ;

Park, GwangLi ;

El Fakhri, Georges ;

Henary, Maged ;

Gioux, Sylvain ;

Frangioni, John V. ;

Choi, Hak Soo .

CHEMICAL COMMUNICATIONS, 2016, 52 (67) :10305-10308

[2] Conductometric Determination of Sulfur Dioxide in Wine Using a Multipumping System Coupled to a Gas-Diffusion cell [J].

Danchana, Kaewta ;

Clavijo, Sabrina ;

Cerda, Victor .

ANALYTICAL LETTERS, 2019, 52 (09) :1363-1378

[3] New fluorescent turn-off probes for highly sensitive and selective detection of SO2 derivatives in a micellar media [J].

Gomez, Marisol ;

Perez, Edwin G. ;

Arancibia, Veronica ;

Iribarren, Constanza ;

Bravo-Diaz, Carlos ;

Garcia-Beltran, Olimpo ;

Aliaga, Margarita E. .

SENSORS AND ACTUATORS B-CHEMICAL, 2017, 238 :578-587

[4] Recent advances in dual-emission ratiometric fluorescence probes for chemo/biosensing and bioimaging of biomarkers [J].

Gui, Rijun ;

Jin, Hui ;

Bu, Xiangning ;

Fu, Yongxin ;

Wang, Zonghua ;

Liu, Qingyun .

COORDINATION CHEMISTRY REVIEWS, 2019, 383 :82-103

[5] Effect of SO2 on sugars, indicators of Maillard reaction, and browning in dried apricots during storage [J].

Hamzaoglu, Fatmagul ;

Turkyilmaz, Meltem ;

Ozkan, Mehmet .

JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2018, 98 (13) :4988-4999

[6] Mitochondria-Targeted Near-Infrared Fluorescent Off-On Probe for Selective Detection of Cysteine in Living Cells and in Vivo [J].

Han, Chunmiao ;

Yang, Huiran ;

Chen, Min ;

Su, Qianqian ;

Feng, Wei ;

Li, Fuyou .

ACS APPLIED MATERIALS & INTERFACES, 2015, 7 (50) :27968-27975

[7] A colorimetric and ratiometric fluorescent probe for sulfite based on an intramolecular cleavage mechanism [J].

Hou, Peng ;

Chen, Song ;

Voitchovsky, Kislon ;

Song, Xiangzhi .

LUMINESCENCE, 2014, 29 (07) :749-753

[8]

Huang Y.Q., 2016, OXIDATIVE MED CELL L

[9] Phototheranostics: Active Targeting of Orthotopic Glioma Using Biomimetic Proteolipid Nanoparticles [J].

Jia, Yali ;

Wang, Xiaobing ;

Hu, Dehong ;

Wang, Pan ;

Liu, Quanhong ;

Zhang, Xuanjun ;

Jiang, Jingying ;

Liu, Xin ;

Sheng, Zonghai ;

Liu, Bin ;

Zheng, Hairong .

ACS NANO, 2019, 13 (01) :386-398

[10] Small-Molecule Fluorescent Probes for Imaging and Detection of Reactive Oxygen, Nitrogen, and Sulfur Species in Biological Systems [J].

Jiao, Xiaoyun ;

Li, Yong ;

Niu, Jinye ;

Xie, Xilei ;

Wang, Xu ;

Tang, Bo .

ANALYTICAL CHEMISTRY, 2018, 90 (01) :533-555

← 1 2 3 4 →