Characterization of intermediate stages in the precipitation of hydroxyapatite at 37 °C

被引：35

作者：

Castro, Filipa ^{[1
]}

Ferreira, Antonio ^{[1
]}

Rocha, Fernando ^{[2
]}

Vicente, Antonio ^{[1
]}

Teixeira, Jose Antonio ^{[1
]}

机构：

[1] Univ Minho, Ctr Biol Engn, IBB, P-4710057 Braga, Portugal

[2] Univ Porto, Fac Engn, LEPAE Lab Proc Environm & Energy Engn, P-4200465 Oporto, Portugal

来源：

CHEMICAL ENGINEERING SCIENCE | 2012年 / 77卷

关键词：

Precipitation; Batch; Calcium phosphate; Supersaturation; Morphology; Aggregation; CALCIUM HYDROXIDE; CARBONATED HYDROXYAPATITE; KINETICS; DISSOLUTION;

D O I：

10.1016/j.ces.2012.01.058

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Precipitation of hydroxyapatite Ca-5(PO4)(3)OH (HAp) was carried out by mixing a saturated calcium hydroxide aqueous solution with an orthophosphoric acid aqueous solution at 37 degrees C. In order to promote optimal conditions for the production of HAp with high yields, mixing of the reaction medium was assured by a novel metal stirrer. Different experimental conditions were studied varying the mixing Ca/P molar ratio from 1 to 1.67. After process optimization, a suspension of HAp particles with pH close to 7 was obtained for a mixing molar ratio Ca/P=1.33. The precipitation process was then characterized as a function of pH and calcium concentration, revealing the existence of three different stages. The precipitate formed in each stage was characterized by scanning electron microscopy and X-ray diffraction. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：150 / 156

页数：7

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