TIM polymorphisms-genetics and function

被引：51

作者：

Lee, J. ^{[1
,2
]}

Phong, B. ^{[1
,2
]}

Egloff, A. M. ^{[3
]}

Kane, L. P. ^{[1
,2
]}

机构：

[1] Univ Pittsburgh, Dept Immunol, Sch Med, Pittsburgh, PA 15261 USA

[2] Univ Pittsburgh, Grad Program Immunol, Sch Med, Pittsburgh, PA 15261 USA

[3] Univ Pittsburgh, Dept Otolaryngol, Sch Med, Pittsburgh, PA 15261 USA

来源：

GENES AND IMMUNITY | 2011年 / 12卷 / 08期

关键词：

transmembrane proteins; asthma; atopy; autoimmunity; HEPATITIS-A VIRUS; T-CELL IMMUNOGLOBULIN; SYSTEMIC-LUPUS-ERYTHEMATOSUS; MUCIN-DOMAIN; RHEUMATOID-ARTHRITIS; KOREAN POPULATION; KIDNEY INJURY; SIGNIFICANT ASSOCIATION; MULTIPLE-SCLEROSIS; CHINESE POPULATION;

D O I：

10.1038/gene.2011.75

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The transmembrane immunoglobulin and mucin domain (TIM) family was identified more than a decade ago. Although the founding member of the family was first described in a rat model of ischemia-reperfusion injury, much of the recent interest in the TIM family members has focused on their potential roles in immunity. There are now a large number of genetic studies that have investigated the possible association of various TIM1 and TIM3 polymorphisms with different diseases. Here, we review this body of literature, and highlight some of the most interesting studies. Genes and Immunity (2011) 12, 595-604; doi:10.1038/gene.2011.75; published online 3 November 2011

引用

页码：595 / 604

页数：10

共 54 条

[1] Shedding of kidney injury molecule-1, a putative adhesion protein involved in renal regeneration [J].

Bailly, V ;

Zhang, ZW ;

Meier, W ;

Cate, R ;

Sanicola, M ;

Bonventre, JV .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (42) :39739-39748

[2] Hepatitis A shifting epidemiology in South-East Asia and China [J].

Barzaga, NG .

VACCINE, 2000, 18 :S61-S64

[3] Up-regulation of IL-18 and predominance of a Th1 immune response is a hallmark of lupus nephritis [J].

Calvani, N ;

Richards, HB ;

Tucci, M ;

Pannarale, G ;

Silvestris, F .

CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2004, 138 (01) :171-178

[4] Hepatitis A outbreaks in China during 2006: application of molecular epidemiology [J].

Cao, Jingyuan ;

Wang, Yue ;

Song, Haiyan ;

Meng, Qingling ;

Sheng, Liping ;

Bian, Tao ;

Mahemuti, Wenqian ;

Yierhali, Ayiguli ;

Omata, Masao ;

Bi, Shengli .

HEPATOLOGY INTERNATIONAL, 2009, 3 (02) :356-363

[5] The polymorphisms of Tim-1 promoter region are associated with rheumatoid arthritis in a Korean population [J].

Chae, SC ;

Park, YR ;

Song, JH ;

Shim, SC ;

Yoon, KS ;

Chung, HT .

IMMUNOGENETICS, 2005, 56 (10) :696-701

[6] The association of TIM-3 gene polymorphism with atopic disease in Korean population [J].

Chae, SC ;

Park, YR ;

Lee, YC ;

Lee, JH ;

Chung, HT .

HUMAN IMMUNOLOGY, 2004, 65 (12) :1427-1431

[7] The polymorphisms of Th1 cell surface gene Tim-3 are associated in a Korean population with rheumatoid arthritis [J].

Chae, SC ;

Parka, YR ;

Shim, SC ;

Yoon, KS ;

Chung, HT .

IMMUNOLOGY LETTERS, 2004, 95 (01) :91-95

[8] The exon 4 variations of Tim-1 gene are associated with rheumatoid arthritis in a Korean population [J].

Chae, SC ;

Song, JH ;

Shim, SC ;

Yoon, KS ;

Chung, HT .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2004, 315 (04) :971-975

[9] Molecular variations in the promoter and coding regions of human Tim-1 gene and their association in Koreans with asthma [J].

Chae, SC ;

Song, JH ;

Heo, JC ;

Lee, YC ;

Kim, JW ;

Chung, HT .

HUMAN IMMUNOLOGY, 2003, 64 (12) :1177-1182

[10] The association of the exon 4 variations of Tim-1 gene with allergic diseases in a Korean population [J].

Chae, SC ;

Song, JH ;

Lee, YC ;

Kim, JW ;

Chung, HT .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2003, 312 (02) :346-350

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