Stimulation of Burn Wound Healing in Rats by Nanosecond Repetitive Pulsed Microwave Radiation

被引:2
|
作者
Gostyukhina, A. A. [1 ,2 ,3 ]
Samoylova, A., V [1 ,3 ,4 ]
Bolshakov, M. A. [1 ,3 ]
Mochalova, V. M. [3 ]
Zaitsev, K., V [2 ]
Kutenkov, O. P. [1 ]
Rostov, V. V. [1 ]
机构
[1] Russian Acad Sci, Inst High Current Elect, Siberian Branch, Tomsk 634055, Russia
[2] Fed Med & Biol Agcy Russia, Fed Sci & Clin Ctr Med Rehabil & Balneol, Tomsk 634009, Russia
[3] Natl Res Tomsk State Univ, Tomsk 634050, Russia
[4] Siberian State Med Univ, Minist Hlth Russian Federat, Tomsk 634050, Russia
关键词
burn wound; nanosecond pulses; microwave radiation; rats;
D O I
10.1134/S1062359022050089
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The effect of nanosecond repetitive pulsed microwave radiation (RPMR, 10 GHz, 100 ns pulse duration, 8 Hz pulse repetition rate, 140 and 1500 W/cm(2) peak power flux density (pPFD)) on the regeneration of burn wounds in rats in dynamics was investigated. It is established that after 4-fold local irradiation of wounds with intensities of 140 and 1500 W/cm(2) at frequency of 8 Hz, wound healing in the control and irradiated groups did not differ significantly (from the 1st day to the 14th day). Statistically significant acceleration of healing of irradiated burn wounds was detected from the 19th day. From the 12th day partial separation of the formed scab was observed. Epithelialization was observed from the 24th day to the 28th day. The effectiveness of RPMR with pPFD of 140 W/cm(2) turned out to be higher in comparison with irradiation with pPFD of 1500 W/cm(2).
引用
收藏
页码:532 / 537
页数:6
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