Absence of JC polyomavirus (JCPyV) viremia in early post-transplant JCPyV nephropathy: A case report

被引：5
作者：
Janphram, Chitimaporn [1 ]
Worawichawong, Suchin [2 ]
Disthabanchong, Sinee [1 ]
Sumethkul, Vasant [1 ]
Rotjanapan, Porpon [3 ]
机构：
[1] Mahidol Univ, Ramathibodi Hosp, Div Nephrol, Dept Med, Bangkok, Thailand
[2] Mahidol Univ, Ramathibodi Hosp, Div Renal Pathol, Dept Pathol, Bangkok, Thailand
[3] Mahidol Univ, Ramathibodi Hosp, Div Infect Dis, Dept Med, Bangkok, Thailand
来源：
TRANSPLANT INFECTIOUS DISEASE | 2017年 / 19卷 / 06期
关键词：
allograft dysfunction; JC virus nephropathy; kidney transplant; VIRUS-ASSOCIATED NEPHROPATHY; RENAL-TRANSPLANTATION; BK; RECIPIENTS; INFECTION;
D O I：
10.1111/tid.12761
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
JC polyomavirus (JCPyV)-associated nephropathy (JCPyVAN) occurs in <3% of PVAN cases after renal transplantation. We report the first confirmed case to our knowledge of JCPyVAN diagnosed by kidney biopsy in the early 6months post transplant in Thailand. In this case report, recovery of renal allograft function was not observed after reduction of immunosuppressive agents and administration of intravenous immunoglobulin and cidofovir. Despite persistent JCPyV viruria, no significant further decline in allograft function was documented at 15months post transplant.
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