A Surprisingly Singular Role for Endophilin in Synaptic Vesicle Recycling

被引:4
作者
Sullivan, Jane M. [1 ]
机构
[1] Univ Washington, Sch Med, Dept Physiol & Biophys, Seattle, WA 98195 USA
关键词
NEUROTRANSMITTER RELEASE; SYNAPTOJANIN; ENDOCYTOSIS; FISSION;
D O I
10.1016/j.neuron.2011.10.025
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Synaptic vesicle endocytosis requires membrane curvature, fission, and uncoating. Endophilin has been proposed to play a role in all three steps, but in this issue of Neuron, De Camilli and colleagues show that at mammalian central synapses it is primarily involved in clathrin uncoating.
引用
收藏
页码:504 / 505
页数:2
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