Cytotoxicity of Ganoderma lucidum triterpenes

被引：131

作者：

Wu, TS ^{[1
]}

Shi, LS

Kuo, SC

机构：

[1] Natl Cheng Kung Univ, Dept Chem, Tainan 701, Taiwan

[2] China Med Coll, Grad Inst Pharmaceut Chem, Taichung, Taiwan

来源：

JOURNAL OF NATURAL PRODUCTS | 2001年 / 64卷 / 08期

关键词：

D O I：

10.1021/np010115w

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new triterpenoids, lucidenic acid N(1) and methyl lucidenate F (2), together with four known compounds, lucidenic acid A, lucidenolactone, lucidenic acid C, and ganoderic acid E, were isolated from the dried fruiting bodies of Ganoderma lucidum. Their struct-es were elucidated by spectral and chemical transformation studies. Among them, lucidenic acid N (1), lucidenic acid A, and ganoderic acid E showed significant cytotoxic activity against Hep G2, Hep G2,2,15, and P-388 tumor cells.

引用

页码：1121 / 1122

页数：2

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