Neuropsychological status of children with newly diagnosed idiopathic childhood epilepsy

被引:13
作者
Jeong, Min Hee [3 ]
Yum, Mi-Sun [3 ]
Ko, Tae-Sung [3 ]
You, Su Jeong [1 ,2 ]
Lee, Eun Hye [3 ]
Yoo, Hanik K. [4 ]
机构
[1] Inje Univ, Dept Pediat, Sanggye Paik Hosp, Coll Med, Seoul 139707, South Korea
[2] Inje Univ, Epilepsy Ctr, Sanggye Paik Hosp, Coll Med, Seoul 139707, South Korea
[3] Univ Ulsan, Dept Pediat, Asan Med Ctr, Coll Med, Seoul 138736, South Korea
[4] Univ Ulsan, Dept Psychiat, Asan Med Ctr, Coll Med, Seoul 138736, South Korea
关键词
Epilepsy; Childhood; IQ; Generalized; Benign childhood epilepsy with centro-temporal spikes; CENTROTEMPORAL SPIKES; NEW-ONSET; PERFORMANCE; SEIZURES; MEMORY;
D O I
10.1016/j.braindev.2010.11.003
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We characterized the neuropsychological status of children with newly diagnosed idiopathic childhood epilepsy and measured differences in IQ between children with different types of epilepsy. The Korean Education Development Institute-Wechsler Intelligence Scale for Children (KEDI-WISC) was administered to 72 patients (35 males and 37 females), of mean age 8.7 +/- 2.6 years, with newly diagnosed idiopathic childhood epilepsy. Of these patients, 22 (30.6%) had generalized epilepsy, 48 (66.7%) localization-related epilepsy, and 2 (2.8%) mixed epilepsy. Children with generalized epilepsy and benign childhood epilepsy with centro-temporal spikes (BCECTS) were of similar verbal IQ and full-scale IQ, although performance IQ was significantly lower in patients with generalized epilepsy. Among children with BCECTS, those with unilateral spikes had higher full-scale and performance IQ scores than those with bilateral spikes. Follow-up studies on large numbers of patients are needed to determine the effects of epilepsy per se, and antiepileptic drugs, on intelligence. (C) 2010 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:666 / 671
页数:6
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