Synthesis of the Azepinoindole Framework via Oxidative Heck (Fujiwara-Moritani) Cyclization

被引：23

作者：

Donets, Pavel A. ^{[1
]}

Van der Eycken, Erik V. ^{[1
]}

机构：

[1] Katholieke Univ Leuven, Dept Chem, LOMAC, B-3001 Louvain, Belgium

来源：

SYNTHESIS-STUTTGART | 2011年 / 13期

关键词：

C-H activation; Heck reaction; palladium; indoles; heterocycles; PALLADIUM-CATALYZED CYCLIZATION; INDOLE-DERIVATIVES; MOLECULAR-OXYGEN; FUNCTIONALIZATION; BENZOQUINONE; ANILIDES; OLEFINS; RING;

D O I：

10.1055/s-0030-1260057

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A catalytic oxidative Heck (Fujiwara-Moritani) cyclization has been evaluated for construction of the azepinoindole framework starting from readily available 3-indoleacetic acid amides. The supporting role of the amide group in the substrate has been demonstrated necessary for the success of the cyclization.

引用

页码：2147 / 2153

页数：7

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