Comparative study of the chemical compositions and antibacterial activity of the essential oils of two lagochilus species (L. Archery, L. Cabulicus) collected from the North Khorasan province of Iran

The present research study reports on the extraction by hydrodistillation and the chemical composition of two Lagochilus species (L. Archery, L. Cabulicus) essential oils and antimicrobial properties from Iran. The chemical composition of the essential oils was determined by gas chromatography coupled to a mass spectrometer. An agar well diffusion method evaluated the antimicrobial effect of the essential oils of the tested species against 3 Escherichia coli, Staphylococcus aureus, and Bacillus atrophaeus. In the essential oils of L. Cabulicus, 30 compounds which constituted 86.65% of the essential oils have been identified, the main constituents of alpha-pinene (36.01%), beta-myrcene (10.21%), Germacrene D (6.03%), Limonene (4.75%) and cis-verbenone (4.73%) were the main components of the essential oils. 21 compounds were identified in the essential oils of L. Aucheri which made up 84.28% of the essential oils. a-pinene (24.74%), beta-myrcene (12.85%), p-cymene (12.10%), Germacrene D (8.85%), Limonene (6.15%) and p-cymene-4-oil (5.23%) constituted the main components of this essential oil. Also, the results of microbial tests against 3 pathogenic bacteria showed significant effects on Staphylococcus aureus and Bacillus atrophaeus, and no effect was observed on Escherichia coli.