A multicentre observational study of intra-operative ventilatory management during general anaesthesia: tidal volumes and relation to body weight

被引：115

作者：

Jaber, S. ^{[1
]}

Coisel, Y. ^{[1
]}

Chanques, G. ^{[1
]}

Futier, E. ^{[2
]}

Constantin, J. -M. ^{[2
]}

Michelet, P. ^{[3
]}

Beaussier, M. ^{[4
]}

Lefrant, J. -Y. ^{[5
]}

Allaouchiche, B. ^{[6
]}

Capdevila, X. ^{[7
]}

Marret, E. ^{[8
]}

机构：

[1] Univ Montpellier I, CHU Montpellier, Anaesthesia & Crit Care Dept B, St Eloi Teaching Hosp,Unite INSERM U1046, Montpellier, France

[2] Ctr Hosp Univ Clermont Ferrand, Hotel Dieu Teaching Hosp, Anaesthesia & Crit Care Dept, Clermont Ferrand, France

[3] Ctr Hosp Univ Marseille, Anaesthesia & Crit Care Dept, St Marguerite Teaching Hosp, Marseille, France

[4] St Antoine Teaching Hosp, AP HP, Anaesthesia & Crit Care Dept, Paris, France

[5] Anaesthesia & Crit Care Dept, Nimes 9, France

[6] Ctr Hosp Univ Lyon, Anaesthesia & Crit Care Dept, Edouard Herriot Teaching Hosp, Lyon, France

[7] CHU Montpellier, Lapeyronie Teaching Hosp, Anaesthesia & Crit Care Dept A, Montpellier, France

[8] Tenon Teaching Hosp, AP HP, Anaesthesia & Crit Care Dept, Paris, France

来源：

ANAESTHESIA | 2012年 / 67卷 / 09期

关键词：

ACUTE LUNG INJURY; RECEIVING MECHANICAL VENTILATION; RESPIRATORY-DISTRESS-SYNDROME; MAJOR COMPLICATIONS; OBESE-PATIENTS; RISK-FACTORS; OXYGENATION; STRATEGIES; SETTINGS;

D O I：

10.1111/j.1365-2044.2012.07218.x

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

We conducted an observational prospective multicenter study to describe the practices of mechanical ventilation, to determine the incidence of use of large intra-operative tidal volumes (= 10 ml.kg-1 of ideal body weight) and to identify patient factors associated with this practice. Of the 2960 patients studied in 97 anaesthesia units from 49 hospitals, volume controlled mode was the most commonly used (85%). The mean (SD) tidal volume was 533 (82) ml; 7.7 (1.3) ml.kg-1 (actual weight) and 8.8 (1.4) ml.kg-1 (ideal body weight)). The lungs of 381 (18%) patients were ventilated with a tidal volume > 10 ml.kg-1 ideal body weight. Being female (OR 5.58 (95% CI 4.207.43)) and by logistic regression, underweight (OR 0.06 (95% CI 0.010.45)), overweight (OR 1.98 (95% CI 1.492.65)), obese (OR 5.02 (95% CI 3.517.16)), severely obese (OR 10.12 (95% CI 5.7917.68)) and morbidly obese (OR 14.49 (95% CI 6.9930.03)) were the significant (p?=?0.005) independent factors for the use of large tidal volumes during anaesthesia.

引用

页码：999 / 1008

页数：10

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