Synthesis of bis(indolyl)methanes using ammonium niobium oxalate (ANO) as an efficient and recyclable catalyst

被引：79

作者：

Mendes, Samuel R. ^{[1
]}

Thurow, Samuel ^{[2
]}

Penteado, Filipe ^{[2
]}

da Silva, Maite S. ^{[1
]}

Gariani, Rogerio A. ^{[1
]}

Perin, Gelson ^{[2
]}

Lenardao, Eder J. ^{[2
]}

机构：

[1] Univ Estado Santa Catarina UDESC, Dept Quim, GAPAM, BR-89219710 Joinville, SC, Brazil

[2] Univ Fed Pelotas UFPel, Lab Sintese Organ Limpa LASOL, BR-96010900 Pelotas, RS, Brazil

来源：

GREEN CHEMISTRY | 2015年 / 17卷 / 08期

关键词：

BISINDOLE ALKALOIDS; CARBOXYLIC-ACIDS; RAPID SYNTHESIS; MILD SYNTHESIS; INDOLES; INDOLE-3-CARBINOL; SONOCHEMISTRY; ACTIVATION; EXPEDIENT; MICROWAVE;

D O I：

10.1039/c5gc00932d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A green and efficient procedure was developed for the synthesis of bis(indolyl) methanes using ammonium niobium oxalate (ANO) NH4[NbO(C2O4)(2)(H2O) x]center dot nH(2)O as the catalyst and water or glycerol as the solvent. Products were obtained in good to excellent yields under conventional heating (water, 50 degrees C) or under sonication (glycerol, 110 degrees C). In the reaction in water, the catalyst was easily reused for further reactions without loss of activity.

引用

页码：4334 / 4339

页数：6

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