Anti-hyperlipidaemic and antioxidant effects of turmeric oil in hyperlipidaemic rats

被引：34
作者：
Ling, Jingjing [1 ]
Wei, Bo [1 ]
Lv, Guangping
Ji, Hui [1 ]
Li, Shaoping
机构：
[1] China Pharmaceut Univ, Dept Pharmacol, Nanjing 210009, Peoples R China
来源：
FOOD CHEMISTRY | 2012年 / 130卷 / 02期
关键词：
Turmeric oil; Hyperlipidaemic rats; Antioxidant activity; Anti-hyperlipidaemic activity; CHROMATOGRAPHY-MASS-SPECTROMETRY; HIGH-FAT DIET; CURCUMA-LONGA L; HYPERCHOLESTEROLEMIC RATS; CHOLESTEROL LEVELS; OXIDATIVE STRESS; BY-PRODUCT; L; COMPONENTS; EXTRACTS;
D O I：
10.1016/j.foodchem.2011.07.039
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
This study was to evaluate the anti-hyperlipidaemic and antioxidant effects of turmeric oil (TO), the supercritical fluid extract from turmeric, in hyperlipidaemic rats induced by a high-fat diet. TO significantly decreased (p < 0.05) the levels of serum total cholesterol, low-density lipoprotein cholesterol, triglyceride, and free fatty acid and increased (p < 0.05) that of high-density lipoprotein cholesterol in this model. It also markedly elevated (p <0.05) the activities of superoxide dismutase and glutathione peroxidase and lowered (p <0.05) maleic dialdehyde activity, to suppress oxidative reactions. Besides, histological morphology examination showed that TO prevented the damage of liver tissues induced by high-fat diet. Thus, the findings indicate that TO might provide protection against cardiovascular diseases. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码：229 / 235
页数：7
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