Nuclear reprogramming by human embryonic stem cells

被引：15

作者：

Surani, MA ^{[1
]}

机构：

[1] Univ Cambridge, Wellcome Trust Canc Res UK, Gurdon Inst, Cambridge CB2 1QN, England

来源：

CELL | 2005年 / 122卷 / 05期

关键词：

D O I：

10.1016/j.cell.2005.08.023

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Embryonic stem cells have two unique properties. They are capable of indefinite self-renewal and, being pluripotent, they can differentiate into all possible cell types, including germ cells. A new study by Cowan et al. (2005) published in Science shows that human embryonic stem cells are able to reprogram the nuclei of fully differentiated human somatic cells, apparently conferring on them a pluripotent state.

引用

页码：653 / 654

页数：2

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