Investigations of Bacteroides spp. towards next-generation probiotics

被引:138
作者
Tan, Huizi [1 ,2 ]
Zhai, Qixiao [1 ,2 ,3 ]
Chen, Wei [1 ,2 ,4 ,5 ]
机构
[1] Jiangnan Univ, State Key Lab Food Sci & Technol, Wuxi 214122, Jiangsu, Peoples R China
[2] Jiangnan Univ, Sch Food Sci & Technol, Wuxi 214122, Jiangsu, Peoples R China
[3] Jiangnan Univ, Int Joint Res Lab Probiot, Wuxi 214122, Jiangsu, Peoples R China
[4] Jiangnan Univ, Natl Engn Res Ctr Funct Food, Wuxi 214122, Jiangsu, Peoples R China
[5] Beijing Technol & Business Univ, Beijing Innovat Ctr Food Nutr & Human Hlth, Beijing 100048, Peoples R China
基金
中国国家自然科学基金;
关键词
Bacteroides; Next-generation probiotics; Inflammation; Immune modulation; XYLANISOLVENS DSM 23964; LACTOBACILLUS-CASEI; 01; VI SECRETION SYSTEMS; GUT MICROBIOTA; BACTERIAL POLYSACCHARIDES; SAFETY EVALUATION; IMMUNE-RESPONSE; DOUBLE-BLIND; IN-VIVO; FRAGILIS;
D O I
10.1016/j.foodres.2018.08.088
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Probiotics play important roles on sustaining or reconstructing the homeostasis of intestinal microbiota, which is one of the key factors in alleviating diseases and maintaining the healthy condition of the host. Preclinical trials indicate that Bacteroides genus is widely considered as source of novel beneficial candidates for attenuating inflammation by regulating lymphocytes and cytokine expression, controlling metabolism and preventing cancer. Furthermore, the first case of authorization of Bacteroides xylanisolvens in food by the European Commission opens the gate for further investigation and application of this promising community. With this paper, we summarized current investigations of discovering beneficial Bacteroides strains, exploring their interaction mechanisms with the host, and evaluating the potential safety risks during commercialization.
引用
收藏
页码:637 / 644
页数:8
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