Screening for Hepatocellular Carcinoma in Patients with Hepatitis B

被引：11
作者：
Sachar, Yashasavi [1 ]
Brahmania, Mayur [1 ,2 ]
Dhanasekaran, Renumathy [3 ]
Congly, Stephen E. [4 ,5 ]
机构：
[1] Western Univ, London Hlth Sci Ctr, Dept Med, Div Gastroenterol, London, ON N6A 5A5, Canada
[2] Western Univ, Schulich Sch Med & Dent, Ctr Qual Innovat & Safety, London, ON N6A 5W9, Canada
[3] Stanford Univ, Dept Med, Div Gastroenterol & Hepatol, Stanford, CA 94305 USA
[4] Univ Calgary, Cumming Sch Med, Dept Med, Div Gastroenterol & Hepatol, Calgary, AB T2N 4Z6, Canada
[5] Univ Calgary, OBrien Inst Publ Hlth, Calgary, AB T2N 4Z6, Canada
来源：
VIRUSES-BASEL | 2021年 / 13卷 / 07期
关键词：
hepatitis B; hepatocellular carcinoma; cost-effectiveness; screening; risk stratification; alpha-fetoprotein; adherence; ultrasound; RANDOMIZED CONTROLLED-TRIAL; AMAP RISK SCORE; VIRAL-HEPATITIS; COST-EFFECTIVENESS; VIRUS-INFECTION; LIVER-CANCER; ALPHA-FETOPROTEIN; SURVEILLANCE; EPIDEMIOLOGY; CIRRHOSIS;
D O I：
10.3390/v13071318
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Chronic hepatitis B (CHB) infection is a significant risk factor for developing hepatocellular carcinoma (HCC). As HCC is associated with significant morbidity and mortality, screening patients with CHB at a high risk for HCC is recommended in an attempt to improve these outcomes. However, the screening recommendations on who to screen and how often are not uniform. Identifying patients at the highest risk of HCC would allow for the best use of health resources. In this review, we evaluate the literature on screening patients with CHB for HCC, strategies for optimizing adherence to screening, and potential risk stratification tools to identify patients with CHB at a high risk of developing HCC.
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页数：16
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