Biological Activity of the Supramolecular Complex of Glycyrrhizic and Salicylic Acids

被引：1

作者：

Babaeva, D. T. ^{[1
]}

Esanov, R. S. ^{[1
]}

Akhunov, A. A. ^{[1
]}

Gafurov, M. B. ^{[1
]}

Khashimova, N. R. ^{[1
]}

Matchanov, A. D. ^{[1
]}

机构：

[1] Acad Sci Uzbek, AS Sadykov Inst Bioorgan Chem, Tashkent, Uzbekistan

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2020年 / 56卷 / 02期

关键词：

supramolecular complex; glycyrrhizic acid; salicylic acid; catalase; peroxidase; superoxide dismutase;

D O I：

10.1007/s10600-020-03006-1

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Supramolecular complexes of glycyrrhizic acid (GA) and salicylic acid (SA) in various mole ratios of 1:1, 2:1, 4:1, and 8:1 were prepared for the first time. Their IR and UV spectra indicated that a complex with SA did form. The supramolecular complex with a 2:1 ratio, which was called DAG-1, had the optimal molecular ratio of GA and SA for high biological activity. DAG-1 at a concentration of 10(-7) M induced antioxidantenzyme (catalase, peroxidase, superoxide dismutase) activity and stimulated cotton growth and development under model chloride salinity conditions.

引用

页码：278 / 281

页数：4

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