Synthesis and Characterization of a New Coumarin-1,2,3-Triazole Diad

被引：0

作者：

Li, Hong-qi ^{[1
]}

Tian, Xiu-juan ^{[1
]}

Chen, Zhen ^{[1
]}

Xiao, Ding ^{[1
]}

Fang, Ning ^{[1
]}

Lv, Yan-xiang ^{[1
]}

Gu, Liang ^{[1
]}

机构：

[1] Donghua Univ, Coll Chem Chem Engn & Biotechnol, Shanghai 201620, Peoples R China

来源：

MATERIALS, MACHINES AND DEVELOPMENT OF TECHNOLOGIES FOR INDUSTRIAL PRODUCTION | 2014年 / 618卷

关键词：

Coumarin; 1,2,3-Triazole; Click chemistry; Synthesis; COUMARIN; DERIVATIVES; INHIBITORS; PROBE; HYBRIDS;

D O I：

10.4028/www.scientific.net/AMM.618.170

中图分类号：

TH [机械、仪表工业];

学科分类号：

0802 ;

摘要：

A new coumarin-1,2,3-triazole diad was designed and synthesized by Pechmann-Duisberg reaction and click chemistry. The three-step synthetic route to the target compound afforded an overall yield of 56%. The structures of the synthesized compounds were characterized by H-1 NMR, C-13 NMR, IR and mass spectrum. The click chemistry provided an ideal approach for synthesis under mild conditions of coumarin-1,2,3-triazole diads which may exhibit excellent biological activities such as antitubercular activity.

引用

页码：170 / 174

页数：5

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