Primary Graft Dysfunction after Heart Transplantation - Unravelling the Enigma

被引：15

作者：

Al-Adhami, Ahmed ^{[1
]}

Singh, Sanjeet Singh Avtaar ^{[1
,2
]}

Das De, Sudeep ^{[3
]}

Singh, Ramesh ^{[4
]}

Panjrath, Gurusher ^{[5
]}

Shah, Amit ^{[6
]}

Dalzell, Jonathan R. ^{[7
]}

Schroder, Jacob ^{[8
]}

Al-Attar, Nawwar ^{[1
,2
]}

机构：

[1] Golden Jubilee Natl Hosp, Dept Cardiothorac Surg, Glasgow, Lanark, Scotland

[2] Univ Glasgow, Inst Cardiovasc & Med Sci ICAMS, Glasgow, Lanark, Scotland

[3] Royal Infirm Edinburgh NHS Trust, Dept Cardiothorac Surg, Edinburgh, Midlothian, Scotland

[4] Inova Hlth Syst, Mech Circulatory Support, Falls Church, VA USA

[5] George Washington Univ Hosp, Heart Failure & Mech Circulatory Support Program, Washington, DC USA

[6] Fiona Stanley Hosp, Adv Heart Failure & Cardiac Transplant Unit, Perth, WA, Australia

[7] Golden Jubilee Natl Hosp, Scottish Natl Adv Heart Failure Serv, Glasgow, Lanark, Scotland

[8] Duke Univ, Div Cardiovasc & Thorac Surg, Heart Transplantat Program, Med Ctr, Durham, NC USA

来源：

CURRENT PROBLEMS IN CARDIOLOGY | 2022年 / 47卷 / 08期

关键词：

TUMOR-NECROSIS-FACTOR; CARDIAC TROPONIN-I; RED-BLOOD-CELL; EXTRACORPOREAL MEMBRANE-OXYGENATION; PERMEABILITY TRANSITION PORE; LEFT-VENTRICULAR HYPERTROPHY; ISCHEMIA-REPERFUSION INJURY; ACUTE MYOCARDIAL-INFARCTION; BRAIN NATRIURETIC PEPTIDE; ARTERY-BYPASS SURGERY;

D O I：

10.1016/j.cpcardiol.2021.100941

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Primary graft dysfunction (PGD) remains the main cause of early mortality following heart transplantation despite several advances in donor preservation techniques and therapeutic strategies for PGD. With that aim of establishing the aetiopathogenesis of PGD and the preferred management strategies, the new consensus definition has paved the way for multiple contemporaneous studies to be undertaken and accurately compared. This review aims to provide a broad-based understanding of the pathophysiology, clinical presentation and management of PGD.

引用

页数：39

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