Mediator Architecture and RNA Polymerase II Interaction

被引：39

作者：

Plaschka, Clemens ^{[1
]}

Nozawa, Kayo ^{[1
]}

Cramer, Patrick ^{[1
]}

机构：

[1] Max Planck Inst Biophys Chem, Dept Mol Biol, Fassberg 11, D-37077 Gottingen, Germany

来源：

JOURNAL OF MOLECULAR BIOLOGY | 2016年 / 428卷 / 12期

基金：

欧洲研究理事会;

关键词：

gene transcription; RNA polymerase II; coactivator; multiprotein complex; TRANSCRIPTION INITIATION; ELONGATION-FACTOR; REPEAT DOMAIN; MINIMAL SET; COMPLEX; MODULE; BINDING; PROTEIN; TFIIS; DISSOCIATION;

D O I：

10.1016/j.jmb.2016.01.028

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Integrated structural biology recently elucidated the architecture of Mediator and its position on RNA polymerase II. Here we summarize these achievements and list open questions on Mediator structure and mechanism. (C) 2016 Elsevier Ltd. All rights reserved.

引用

页码：2569 / 2574

页数：6

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