Spontaneous recovery of immune checkpoint inhibitor-induced thyroiditis with high free T4 level: A case report

被引：0

作者：

Hagiwara, Rie ^{[1
]}

Suzuki, Daisuke ^{[1
]}

Tonezawa, Shiori ^{[1
]}

Saikawa, Rika ^{[1
]}

Funazaki, Shunsuke ^{[1
]}

Yoshida, Masashi ^{[1
]}

Washino, Satoshi ^{[2
]}

Miyagawa, Tomoaki ^{[2
]}

Hara, Kazuo ^{[1
]}

Yamada, Hodaka ^{[1
]}

机构：

[1] Jichi Med Univ, Saitama Med Ctr, Dept Endocrinol & Metab, Saitama, Japan

[2] Jichi Med Univ, Saitama Med Ctr, Dept Urol, Saitama, Japan

来源：

CLINICAL CASE REPORTS | 2021年 / 9卷 / 09期

关键词：

high CRP level; high free T4 level; immune checkpoint inhibitors (ICI); thyroiditis; without steroids; ADVERSE EVENTS;

D O I：

10.1002/ccr3.4781

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We describe a case of severe hyperthyroidism with high free thyroxine and C-reactive protein levels, wherein thyroid function rapidly improved without treatment. In a similar case, conservative management with imaging follow-up can be considered.

引用

页数：5

共 22 条

[1] Management of immune-related adverse events in endocrine organs induced by immune checkpoint inhibitors: clinical guidelines of the Japan Endocrine Society [J].

Arima, Hiroshi ;

Iwama, Shintaro ;

Inaba, Hidefumi ;

Ariyasu, Hiroyuki ;

Makita, Noriko ;

Otsuki, Michio ;

Kageyama, Kazunori ;

Imagawa, Akihisa ;

Akamizu, Takashi .

ENDOCRINE JOURNAL, 2019, 66 (07) :581-586

[2] Incidence of Endocrine Dysfunction Following the Use of Different Immune Checkpoint Inhibitor Regimens A Systematic Review and Meta-analysis [J].

Barroso-Sousa, Romualdo ;

Barry, William T. ;

Garrido-Castro, Ana C. ;

Hodi, F. Stephen ;

Min, Le ;

Krop, Ian E. ;

Tolaney, Sara M. .

JAMA ONCOLOGY, 2018, 4 (02) :173-182

[3] Thyroid computed tomography imaging: pictorial review of variable pathologies [J].

Bin Saeedan M. ;

Aljohani I.M. ;

Khushaim A.O. ;

Bukhari S.Q. ;

Elnaas S.T. .

Insights into Imaging, 2016, 7 (4) :601-617

[4] Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline [J].

Brahmer, Julie R. ;

Lacchetti, Christina ;

Schneider, Bryan J. ;

Atkins, Michael B. ;

Brassil, Kelly J. ;

Caterino, Jeffrey M. ;

Chau, Ian ;

Ernstoff, Marc S. ;

Gardner, Jennifer M. ;

Ginex, Pamela ;

Hallmeyer, Sigrun ;

Chakrabarty, Jennifer Holter ;

Leighl, Natasha B. ;

Mammen, Jennifer S. ;

McDermott, David F. ;

Naing, Aung ;

Nastoupil, Loretta J. ;

Phillips, Tanyanika ;

Porter, Laura D. ;

Puzanov, Igor ;

Reichner, Cristina A. ;

Santomasso, Bianca D. ;

Seigel, Carole ;

Spira, Alexander ;

Suarez-Almazor, Maria E. ;

Wang, Yinghong ;

Weber, Jeffrey S. ;

Wolchok, Jedd D. ;

Thompson, John A. .

JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (17) :1714-+

[5] Autoimmune complications of immunotherapy: pathophysiology and management [J].

Chan, Karmela K. ;

Bass, Anne R. .

BMJ-BRITISH MEDICAL JOURNAL, 2020, 369

[6] Programmed death-ligand 1 overexpression is a prognostic marker for aggressive papillary thyroid cancer and its variants [J].

Chowdhury, Subrata ;

Veyhl, Joe ;

Jessa, Fatima ;

Polyakova, Olena ;

Alenzi, Ahmed ;

MacMillan, Christina ;

Ralhan, Ranju ;

Walfish, Paul G. .

ONCOTARGET, 2016, 7 (22) :32318-32328

[7] Managing Adverse Events With Immune Checkpoint Agents [J].

Dadu, Ramona ;

Zobniw, Chrystia ;

Diab, Adi .

CANCER JOURNAL, 2016, 22 (02) :121-129

[8] Pembrolizumab-Induced Thyroiditis: Comprehensive Clinical Review and Insights Into Underlying Involved Mechanisms [J].

Delivanis, Danae A. ;

Gustafson, Michael P. ;

Bornschlegl, Svetlana ;

Merten, Michele M. ;

Kottschade, Lisa ;

Withers, Sarah ;

Dietz, Allan B. ;

Ryder, Mabel .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2017, 102 (08) :2770-2780

[9] Pembrolizumab-Induced Thyroiditis [J].

Imblum, Brittney A. ;

Baloch, Zubair W. ;

Fraker, Douglas ;

LiVolsi, Virginia A. .

ENDOCRINE PATHOLOGY, 2019, 30 (02) :163-167

[10] Immune-Related Thyroiditis with Immune Checkpoint Inhibitors [J].

Iyer, Priyanka C. ;

Cabanillas, Maria E. ;

Waguespack, Steven G. ;

Hu, Mimi I. ;

Thosani, Sonali ;

Lavis, Victor R. ;

Busaidy, Naifa L. ;

Subudhi, Sumit K. ;

Diab, Adi ;

Dadu, Ramona .

THYROID, 2018, 28 (10) :1243-1251

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