Application of metal nanoparticles in confocal laser scanning microscopy:: improved resolution by optical field enhancement

被引:36
作者
Alschinger, M [1 ]
Maniak, M [1 ]
Stietz, F [1 ]
Vartanyan, T [1 ]
Träger, F [1 ]
机构
[1] Univ Kassel, CINSAT, D-34132 Kassel, Germany
来源
APPLIED PHYSICS B-LASERS AND OPTICS | 2003年 / 76卷 / 07期
关键词
D O I
10.1007/s00340-003-1182-y
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We describe experiments in which the field enhancement by metal nanoparticles that accompanies surface plasmon excitation has been exploited in confocal laser scanning microscopy. The objective was to make use of the rapid decay of the enhanced light field with distance from the nanoparticles to increase the longitudinal resolution, by confining the emission of fluorescence light to the immediate vicinity of the contact area between the substrate and the objects under study. We demonstrate that the increased longitudinal resolution is accompanied by a better lateral resolution if the imaged objects have a curved surface.
引用
收藏
页码:771 / 774
页数:4
相关论文
共 20 条
[1]   Laser-based method for fabricating monodisperse metallic nanoparticles [J].
Bosbach, J ;
Martin, D ;
Stietz, F ;
Wenzel, T ;
Träger, F .
APPLIED PHYSICS LETTERS, 1999, 74 (18) :2605-2607
[2]   Surface-enhanced Raman scattering [J].
Campion, A ;
Kambhampati, P .
CHEMICAL SOCIETY REVIEWS, 1998, 27 (04) :241-250
[3]  
HAUGLAND RP, 2002, HDB FLUOREXCENT PROB
[4]  
Holland L., 1970, VACUUM DEPOSITION TH
[5]   Simultaneous topographical and optical characterization of near-field optical aperture probes by way of imaging fluorescent nanospheres [J].
Höppener, C ;
Molenda, D ;
Fuchs, H ;
Naber, A .
APPLIED PHYSICS LETTERS, 2002, 80 (08) :1331-1333
[6]   Single molecule detection using surface-enhanced Raman scattering (SERS) [J].
Kneipp, K ;
Wang, Y ;
Kneipp, H ;
Perelman, LT ;
Itzkan, I ;
Dasari, R ;
Feld, MS .
PHYSICAL REVIEW LETTERS, 1997, 78 (09) :1667-1670
[7]   Surface-enhanced Raman scattering and biophysics [J].
Kneipp, K ;
Kneipp, H ;
Itzkan, I ;
Dasari, RR ;
Feld, MS .
JOURNAL OF PHYSICS-CONDENSED MATTER, 2002, 14 (18) :R597-R624
[8]  
Kreibig U., 1995, OPTICAL PROPERTIES M
[9]   ENHANCED DYE FLUORESCENCE OVER SILVER ISLAND FILMS - ANALYSIS OF THE DISTANCE DEPENDENCE [J].
KUMMERLEN, J ;
LEITNER, A ;
BRUNNER, H ;
AUSSENEGG, FR ;
WOKAUN, A .
MOLECULAR PHYSICS, 1993, 80 (05) :1031-1046
[10]   Characterization of SiO2-overcoated silver-island films as substrates for surface-enhanced Raman scattering [J].
Lacy, WB ;
Williams, JM ;
Wenzler, LA ;
Beebe, TP ;
Harris, JM .
ANALYTICAL CHEMISTRY, 1996, 68 (06) :1003-1011