Zebrafish: A Versatile Animal Model for Fertility Research

被引:74
作者
Hoo, Jing Ying [1 ,2 ,3 ]
Kumari, Yatinesh [4 ]
Shaikh, Mohd Farooq [4 ]
Hue, Seow Mun [2 ]
Goh, Bey Hing [1 ,5 ,6 ]
机构
[1] Monash Univ Malaysia, Jeffrey Cheah Sch Med & Hlth Sci, Biomed Res Lab, Jalan Lagoon Selatan, Bandar Sunway 47500, Selangor Darul, Malaysia
[2] Monash Univ Malaysia, Sch Sci, Jalan Lagoon Selatan, Bandar Sunway 47500, Selangor, Malaysia
[3] Sunway Coll, Jalan Univ, Petaling Jaya 46150, Selangor, Malaysia
[4] Monash Univ Malaysia, Jeffrey Cheah Sch Med & Hlth Sci, Neuropharmacol Res Lab, Jalan Lagoon Selatan, Bandar Sunway 47500, Selangor, Malaysia
[5] Monash Univ Malaysia, Sch Pharm, Novel Bacteria & Drug Discovery Res Grp, Jalan Lagoon Selatan, Bandar Sunway 47500, Selangor Darul, Malaysia
[6] Univ Phayao, Sch Pharmaceut Sci, Ctr Hlth Outcomes Res & Therapeut Safety Cohorts, Phayao 56000, Thailand
关键词
ANTI-MULLERIAN HORMONE; ENVIRONMENTALLY RELEVANT CONCENTRATIONS; CORTICOSTEROID STRESS AXIS; MESSENGER-RNA EXPRESSION; DANIO-RERIO; LUTEINIZING-HORMONE; FEMALE ZEBRAFISH; REPRODUCTIVE-PERFORMANCE; GENE-EXPRESSION; KISS1; NEURONS;
D O I
10.1155/2016/9732780
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The utilization of zebrafish in biomedical research is very common in the research world nowadays. Today, it has emerged as a favored vertebrate organism for the research in science of reproduction. There is a significant growth in amount numbers of scientific literature pertaining to research discoveries in reproductive sciences in zebrafish. It has implied the importance of zebrafish in this particular field of research. In essence, the current available literature has covered from the very specific brain region or neurons of zebrafish, which are responsible for reproductive regulation, until the gonadal level of the animal. The discoveries and findings have proven that this small animal is sharing a very close/similar reproductive system with mammals. More interestingly, the behavioral characteristics and along with the establishment of animal courtship behavior categorization in zebrafish have laid an even stronger foundation and firmer reason on the suitability of zebrafish utilization in research of reproductive sciences. In view of the immense importance of this small animal for the development of reproductive sciences, this review aimed at compiling and describing the proximate close similarity of reproductive regulation on zebrafish and human along with factors contributing to the infertility, showing its versatility and its potential usage for fertility research.
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页数:20
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