Executive Functions and Prader-Willi Syndrome: Global Deficit Linked With Intellectual Level and Syndrome-Specific Associations

被引：25

作者：

Chevalere, Johann ^{[1
]}

Postal, Virginie ^{[1
]}

Jauregui, Joseba ^{[2
,3
]}

Copet, Pierre ^{[3
]}

Laurier, Virginie ^{[3
]}

Thuilleaux, Denise ^{[3
]}

机构：

[1] Univ Bordeaux, Lab Psychol, F-33076 Bordeaux, France

[2] Euskal Herriko Unibertsitatea, San Sebastian, Spain

[3] Hop Marin, Hendaye, France

来源：

AJIDD-AMERICAN JOURNAL ON INTELLECTUAL AND DEVELOPMENTAL DISABILITIES | 2015年 / 120卷 / 03期

关键词：

executive function; Prader-Willi syndrome; intellectual disability; assessment tasks; WORKING-MEMORY CAPACITY; BEHAVIOR; ABILITIES; ADULTS; INDIVIDUALS; IMPAIRMENT; DISORDERS; ATTENTION; ANGELMAN; DELETION;

D O I：

10.1352/1944-7558-120.3.215

中图分类号：

G76 [特殊教育];

学科分类号：

040109 ;

摘要：

The aim of this study was to support the growing evidence suggesting that Prader-Willi Syndrome (PWS) might present with an impairment of executive functions (EFs) and to investigate whether this impairment is specific to patients with PWS or due to their intellectual disability (ID). Six tasks were administered to assess EFs (inhibition, switching, updating, cognitive estimation, and planning) to 17 patients with PWS and 17 age-matched healthy individuals. Performance was significantly impaired in the PWS group on all EFs and after controlling for IQ level, intergroup differences remained only for switching and cognitive estimation. In conclusion, PWS seems to be associated with a global impairment of EFs that appears to be closely linked with intellectual impairment but also with the PWS itself.

引用

页码：215 / 229

页数：15

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