Health-related quality of life in patients with alveolar echinococcosis: a cross-sectional study

被引:11
作者
Schmidberger, Julian [1 ]
Weimer, Henriette [1 ]
Schlingeloff, Patrycja [1 ]
Kratzer, Wolfgang [1 ]
Gruener, Beate [2 ]
Barth, Thomas F. E.
Baumann, Sven
Henne-Bruns, Doris
Graeter, Tilmann
Hillenbrand, Andreas
Kaltenbach, Tanja
Theis, Frauke
机构
[1] Ulm Univ Hosp, Dept Internal Med 1, Albert Einstein Allee 23, D-89081 Ulm, Germany
[2] Ulm Univ Hosp, Dept Internal Med 3, Albert Einstein Allee 23, D-89081 Ulm, Germany
关键词
Alveolar echinococcosis; Echinococcus multilocularis; Health-related quality of life; Healthy control group; SF-36; questionnaire; RISK-FACTORS; MULTILOCULARIS; BENZIMIDAZOLES; POPULATIONS; INFECTION; DISEASE;
D O I
10.1007/s15010-018-1219-0
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The Alveolar echinococcosis (AE) is a rare zoonosis caused by the parasite Echinococcus multilocularis. To date, nothing is known about the health-related quality of life (HRQoL) in patients with AE. The aim of the study was to evaluate the HRQoL in patients with AE in comparison of the healthy population. We used the 36-Item Short Form Health Survey (SF-36) questionnaire to evaluate the HRQoL. The SF-36 scales have a range of 0-100 (0 represents the worst and 100 the most favourable state of health). SAS Version 9.2 was used for the statistical analysis of AE-cases (n = 30) and the healthy control group (n = 35). The analysis showed that the HRQoL in people with AE is reduced in comparison with the control population. The study group consisted of 15 (50.0%) men and 15 (50.0%) women; the control group of 16 (45.7%) men and 19 (54.3%) women. The mean age was 55.73 +/- 16.65 years, while that of the control group was 54.57 +/- 15.34 years. The physical quality of life in patients with AE (45.21 +/- 11.42) was not significantly less than that of the control group (50.54 +/- 10.52); p = 0.0568. Nevertheless, AE-patients show lower SF-36 scores for the physical quality of life. For the mental quality of life, patients with AE had a significantly lower score (45.46 +/- 10.57) than the control group (51.57 +/- 9.04); p = 0.0154. The HRQoL in people with AE is reduced in comparison with a control population. Assessment of the physical and mental quality of life in patients with AE may help to evaluate the patient outcome.
引用
收藏
页码:67 / 75
页数:9
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