Dynamic interactions between the cellular components of the heart and the extracellular matrix

被引：16
作者：
Borg, Thomas K. [1 ]
Baudino, Troy A. [2 ]
机构：
[1] Med Univ S Carolina, Dept Regenerat Med & Cell Biol, Charleston, SC 29425 USA
[2] Texas A&M Hlth Sci Ctr, Dept Med, Coll Med, Div Mol Cardiol, Temple, TX 76504 USA
来源：
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY | 2011年 / 462卷 / 01期
关键词：
Extracellular matrix; Myocytes; Fibroblasts; Endothelial cells; Heart; RENIN-ANGIOTENSIN SYSTEM; CARDIAC FIBROBLASTS; CAPILLARY DENSITY; INTEGRINS; METALLOPROTEINASES; ANGIOGENESIS; ORGANIZATION; CONNECTIONS; MECHANISMS; MYOCYTES;
D O I：
10.1007/s00424-011-0940-7
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
The heart is composed of both cellular and acellular components that act in a dynamic fashion from birth to death. The cellular components consist of myocytes, fibroblasts, and vascular cells, including endothelium and smooth muscle. Changes in these components are intimately associated with function by altering the mechanical, chemical, and electrical properties of the heart. In future investigations, it will be important to examine these interactions as dynamic changes in response to physiological signals.
引用
收藏
页码：69 / 74
页数：6
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