BSACI guidelines for the management of rhinosinusitis and nasal polyposis

被引:156
作者
Scadding, G. K. [2 ]
Durham, S. R. [3 ]
Mirakian, R. [1 ]
Jones, N. S. [4 ]
Drake-Lee, A. B. [5 ]
Ryan, D. [6 ]
Dixon, T. A. [7 ]
Huber, P. A. J. [8 ]
Nasser, S. M. [1 ]
机构
[1] Univ Cambridge, NHS Fdn Trust, Allergy Clin, Cambridge CB2 0QQ, England
[2] Royal Natl Throat Nose & Ear Hosp, London WC1X 8DA, England
[3] Univ London Imperial Coll Sci Technol & Med, Dept Upper Resp Med, London NHL1, England
[4] Queens Med Ctr, Dept Otolaryngol Head & Neck Surg, Nottingham NG7 2UH, England
[5] Univ Hosp Birmingham, Edgbaston, Birmingham, England
[6] Woodbrook Med Ctr, Loughborough, Leics, England
[7] Royal Liverpool & Broadgreen Univ Hosp, NHS Trust, Liverpool, Merseyside, England
[8] British Soc Allergy & Clin Immunol, London, England
基金
英国医学研究理事会;
关键词
allergen; anti-IgE; antihistamine; anti-leukotriene; aspirin; aspirin desensitization; BSACI; child; Churg-Strauss; computerized tomography (CT); corticosteroid; decongestant; fungal rhinosinusitis; guideline; IgE; immunotherapy; magnetic resonance (MRI); nasal polyps; nitric oxide; occupational; rhinosinusitis; sinusitis; skin prick test; surgery;
D O I
10.1111/j.1365-2222.2007.02889.x
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
This guidance for the management of patients with rhinosinusitis and nasal polyposis has been prepared by the Standards of Care Committee (SOCC) of the British Society for Allergy and Clinical Immunology (BSACI). The recommendations are based on evidence and expert opinion and are evidence graded. These guidelines are for the benefit of both adult physicians and paediatricians treating allergic conditions. Rhinosinusitis implies inflammation of the nose and sinuses which may or may not have an infective component and includes nasal polyposis. Acute rhinosinusitis lasts up to 12 weeks and resolves completely. Chronic rhinosinusitis persists over 12 weeks and may involve acute exacerbations. Rhinosinusitis is common, affecting around 15% of the population and causes significant reduction in quality of life. The diagnosis is based largely on symptoms with confirmation by nasendoscopy. Computerized tomography scans and magnetic resonance imaging are abnormal in approximately one third of the population so are not recommended for routine diagnosis but should be reserved for those with acute complications, diagnostic uncertainty or failed medical therapy. Underlying conditions such as immune deficiency, Wegener's granulomatosis, Churg-Strauss syndrome, aspirin hypersensitivity and allergic fungal sinusitis may present as rhinosinusitis. There are few good quality trials in this area but the available evidence suggests that treatment is primarily medical, involving douching, corticosteroids, antibiotics, anti-leukotrienes, and anti-histamines. Endoscopic sinus surgery should be considered for complications, anatomical variations causing local obstruction, allergic fungal disease or patients who remain very symptomatic despite medical treatment. Further well conducted trials in clearly defined patient groups are needed to improve management.
引用
收藏
页码:260 / 275
页数:16
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