Pharmacoproteomics:: Advancing the efficacy and safety of regenerative therapeutics

被引：23

作者：

Arrell, D. K.

Niederlaender, N. J.

Perez-Terzic, C.

Chung, S.

Behfar, A.

Terzic, A. ^{[1
]}

机构：

[1] Mayo Clin, Coll Med, Marriott Heart Dis Res Program,Dept Med, Div Cardiovasc Dis, Rochester, MN 55905 USA

[2] Mayo Clin, Coll Med, Marriott Heart Dis Res Program,Dept Mol Pharmacol, Div Cardiovasc Dis, Rochester, MN USA

[3] Mayo Clin, Coll Med, Marriott Heart Dis Res Program,Dept Med Genet, Div Cardiovasc Dis, Rochester, MN USA

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 2007年 / 82卷 / 03期

关键词：

D O I：

10.1038/sj.clpt.6100310

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Proteomic analyses encompass a suite of high-throughput technologies for large- scale separation and identification of proteins responsible for execution of physiological processes. As such, proteomics is ideally suited to dissecting developmental complexity and dynamics, an understanding of which is vital to the realization of regenerative therapeutic medicine. Pharmacoproteomics is increasingly targeting characterization of regenerative therapeutic strategies. A perspective on the application of proteomics to further our understanding of cardiac regenerative medicine, in concert with guided cardiogenic programming, is delineated herein.

引用

页码：316 / 319

页数：4

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