Silver-Based Chemical Device as an Adjunct of Domestic Oral Hygiene: A Study on Periodontal Patients

被引:60
作者
Candotto, Valentina [1 ]
Lauritano, Dorina [2 ]
Carinci, Francesco [3 ]
Bignozzi, Carlo Alberto [4 ]
Pazzi, Daniele [4 ]
Cura, Francesca [5 ]
Severino, Marco [6 ]
Scarano, Antonio [7 ,8 ]
机构
[1] Univ Milan, Dept Biomed Surg & Dent Sci, I-20122 Milan, Italy
[2] Univ Milano Bicocca, Ctr Neurosci Milan, Dept Med & Surg, I-20900 Milan, Italy
[3] Univ Ferrara, Dept Morphol Surg & Expt Med, I-44121 Ferrara, Italy
[4] Univ Ferrara, Dept Chem & Pharmaceut Sci, I-44121 Ferrara, Italy
[5] Univ Bologna, Dept Expt Diagnost & Specialty Med, I-40126 Bologna, Italy
[6] Univ Aquila, Dept Life, I-67100 Laquila, Italy
[7] CeSi Met Univ Chieti Pescara, Dept Oral Sci Nano & Biotecnol, I-66100 Chieti, Italy
[8] CeSi Met Univ Chieti Pescara, I-66100 Chieti, Italy
关键词
chronic periodontitis; bacterial load; oral biofilm; red complex; ZINC PLUS OCTENIDINE; TITANIUM-DIOXIDE; PCR ANALYSIS; EFFICACY; THERAPY; DISEASE; MANAGEMENT; BIOFILM; MARKERS;
D O I
10.3390/ma11081483
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
The use of chemical devices for periodontitis treatment has led to new strategies aiming primarily to control infections. Over the last few years, new chemical devices have been subjected to many scientific and medical studies. The purpose of the present study was to assess the effect of a new silver based chemical devices gel named "Hydrosilver Plus Gel", abbreviated here as Hydrosilver, on the pathogenic microorganisms, using Polymerase Chain Reaction (PCR) for microbiological analysis. Materials and methods: Ten patients with a diagnosis of chronic periodontitis in the age group >25 years were selected. None of these patients had received any surgical or non-surgical periodontal therapy, and demonstrated radiographic evidence of moderate bone loss. After scaling and root planning, patients received Hydrosilver to be used at home. Four non-adjacent sites in separate quadrants were selected in each patient for monitoring, based on criteria that the sites localise chronic periodontitis. Microbial analysis was analysed at baseline and at Day 15. SPSS program was used for statistical purposes and a paired samples correlation was performed at the end of the observation period. Results: Mean amounts of bacterial loading before and after Hydrosilver treatment reduced statistically significantly (p = 0.002). Conclusions: The present study demonstrated that Hydrosilver has a good impact on oral biofilm. Additional studies are needed to detect the efficacy of this chemical device.
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页数:7
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