Embryo freezing after intracytoplasmic sperm injection

被引：11

作者：

Van den Abbeel, E ^{[1
]}

Camus, M ^{[1
]}

Joris, H ^{[1
]}

Van Steirteghem, A ^{[1
]}

机构：

[1] Free Univ Brussels, Univ Hosp, Ctr Reprod Med, B-1090 Brussels, Belgium

来源：

MOLECULAR AND CELLULAR ENDOCRINOLOGY | 2000年 / 169卷 / 1-2期

关键词：

human; embryo; ICSI; freezing;

D O I：

10.1016/S0303-7207(00)00351-8

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

This study reports on the safety and efficiency of the cryopreservation of human embryos obtained after intracytoplasmic sperm injection. For this, we evaluated the morphological survival, the capacity of the surviving embryo to develop further in vitro and in vivo. After freezing-thawing embryos obtained after ICSI, 40% of the embryos do not survive the cryopreservation procedure. After selective transfer of further cleaving frozen-thawed embryos, pregnancy loss was 31% (subclinical pregnancy rate of 13% and miscarriage rate of 18%). As a result the livebirth rate per transferred embryos and per thawed embryo was 7 and 3% respectively. Obstetric outcome as well as further follow-up of the children born indicate that cryopreservation of ICSI embryos is a safe procedure, long term follow-up of the children born however is still warranted. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：49 / 54

页数：6

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